M2 PRESSWIRE-August 26, 2019-: Retinal Vein Occlusion
(RVO) Market 2019 Global Analysis, Size, Share, Growth, Leading Players, Merger, Acquisition, Opportunity, Competitive Landscape with Regional Outlook To 2023
Graybug Vision, a clinical stage pharmaceutical company developing potentially transformative long-acting therapies for ocular diseases including wet age-related macular degeneration (AMD), diabetic macular oedema (DME), retinal vein occlusion
(RVO), and primary open angle glaucoma, has secured an USD80m Series C financing, it was reported yesterday.
The US Food and Drug Administration (FDA) has approved the Chemistry, Manufacturing and Controls (CMC) Prior-Approval Supplement (PAS) for the EYLEA (aflibercept) Injection prefilled syringe to treat neovascular (wet) age-related macular degeneration (Wet AMD), macular edema following retinal vein occlusion
(RVO), diabetic macular edema (DME) and diabetic retinopathy (DR).
Eylea, a vascular endothelial growth factor, is already approved four retinal conditions: neovascular wet age-related macular degeneration, macular edema following retinal vein occlusion
, diabetic macular edema and diabetic retinopathy.
Kodiak Sciences announced positive interim results from the ongoing Phase 1b study of KSI-301, its investigational intravitreal anti-VEGF antibody biopolymer conjugate in patients with anti-VEGF treatment-naive neovascular age-related macular degeneration, diabetic macular edema, and macular edema due to retinal vein occlusion
. Across all three diseases under study, strong improvements in vision and retinal anatomy were observed over 12 weeks.
Among patients on filgotinib, four uncomplicated herpes zoster cases and one retinal vein occlusion
were reported, but there were no opportunistic infections, active tuberculosis, malignancies, gastrointestinal perforations, or deaths.
Keywords: Avastin, Bevacizumab, Branch retinal vein occlusion
, Intravitreal injections, Vascular endothelial growth factor.
Retinal vein occlusion
(RVO) is a common retinal vascular disease, and often contributes to the occurrence of visual decline or loss, especially for middle-aged or elderly individuals (1).
The ocular manifestations of anaemia are dry eye, conjunctival haemorrhage, lid haematoma, orbital haemorrhage, retinal haemorrhage, subhyaloid haemorrhage, central retinal vein occlusion
, vitreous haemorrhage, optic disc oedema and optic neuropathy.
Unlike classic central retinal vein occlusion
, patients suffering from this disease are usually healthy and younger than 50 years of age.
Objective: To determine the effectiveness of radial optic neurotomy as a treatment modality for ischemic central retinal vein occlusion