reverse transcriptase

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reverse transcriptase

n.
A polymerase that catalyzes the formation of DNA on an RNA template, found in the retroviruses and in certain other viruses, such as hepatitis B virus.

reverse transcriptase

(trænˈskrɪpteɪz)
n
(Biochemistry) an enzyme present in retroviruses that copies RNA into DNA, thus reversing the usual flow of genetic information in which DNA is copied into RNA

reverse′ tran•scrip′tase

(trænˈskrɪp teɪs, -teɪz)
n.
a retrovirus enzyme that synthesizes DNA from viral RNA, the reverse of the usual DNA-to-RNA replication: used in genetic engineering.
[1970–75]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.reverse transcriptase - a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses
polymerase - an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA
References in periodicals archive ?
Putting equal emphasis on pathogens and host biology, they discuss such topics as the uniqueness of bats, bat coronaviruses, bats and reverse transcribing RNA and DNA viruses, bat reoviruses anthropogenic epidemics: the ecology of bat-borne viruses and the human role in their emergence, whether bats are really special as viral reservoirs, animal models of recently emerged bat-borne viruses, bat genomics, and bat immunology.
Because of difficulties with reverse transcribing the entire SINV-3 genome (wild type or recombinant), 3 regions of the SINV-3 genome were reverse transcribed and amplified to verify transcript production.
Difficulties in reverse transcribing the entire genome and ligating the full-length SINV-3 cDNA into a vector forced us to use an alternative method to produce a full-length clone of the SINV-3 genome.

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