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An RNA molecule that acts as a catalyst, especially for the cleavage of RNA strands at specific sites.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) an RNA molecule capable of catalysing a chemical reaction, usually the cleavage of another RNA molecule
[C20: from ribo(nucleic acid) + (en)zyme]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈraɪ bəˌzaɪm)
a segment of RNA that can act as a catalyst.
[1985–90; ribo(some) + (en)zyme]
ri`bo•zy′mal, adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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References in periodicals archive ?
The report compares RNAi with other antisense approaches using oligonucleotides, aptamers, ribozymes, peptide nucleic acid and locked nucleic acid.
Non-proteinous enzymes are called ribozymes which are catalytic Ribonucleic Acid (RNA) molecules.
Breaker, "Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes," Nature Biotechnology, vol.
RNA self-ligation: from oligonucleotides to full length ribozymes. Biochimie.
For several group I intron ribozymes, folding and catalysis activate the ions of [Mg.sup.2+], but not [Mn.sup.2+].
RNAs are molecules more druggable than proteins, because their targeting is mainly based on nucleic acid complementarity; therefore, an RNA-based drug would be quite easy to design and inexpensive to synthesize (i.e., ASOs, ribozymes, and aptamers) [14].
Cech, "The chemical repertoire of natural ribozymes," Nature, vol.
Ungefroren et al., "Functional disruption of IEX-1 expression by concatemeric hammerhead ribozymes alters growth properties of 293 cells," FEBS Letters, vol.
The sncRNAs can be divided into microRNAs (miRNAs), small interfering RNAs (siRNAs), snoRNAs, snRNAs, PIWI-interacting RNAs (piRNAs), ribozymes, and telomere-associated RNAs (TERC), circular RNAs (circRNAs), and other sncRNAs.
Analysis of a mitochondrial apoptotic pathway using Bid-targeted ribozymes in human MCF7 cells in the absence of a caspase-3-dependent pathway.