Also found in: Medical, Wikipedia.


A bisphosphonate drug, C7H11NO7P2, that inhibits bone resorption and is used in the form of its sodium salt to treat and prevent osteoporosis in postmenopausal women.

[Perhaps (py)ri(dine) + -se-, origin unknown + (hy)dr(oxy) + (bisphosph)onate.]

risedronate, risedronate sodium

(USAN), risedronic acid (INN) n risedronato, risedronato sódico, ácido risedrónico (INN)
References in periodicals archive ?
DENVER--The anabolic agent teriparatide reduced the risk of clinical vertebral fractures in women with osteoporosis when compared with the antiresorptive agent risedronate, and the results held up across groups of women with varying fracture histories in a post hoc analysis of data from the VERO trial.
The sBLA is supported by a Phase 3 randomized, double-blind, double-dummy, active-controlled study evaluating the safety and efficacy of Prolia compared with risedronate in patients receiving glucocorticoid treatment.
This guideline update focuses on treatment with bisphosphonates (alendronate, risedronate, ibandronate, zoledronic acid) and denosumab.
United States-based Amgen has revealed positive top-line results in a phase three study of Prolia (denosumab) compared with risedronate in patients receiving glucocorticoid treatment, it was reported yesterday.
14 In recent years, bisphosphonates are widely used for treatment of osteoporosis, such as Alendronate, Risedronate and Zoledronic et al.
As a member of the new generation of osteoporosis drugs, risedronate sodium is used for the treatment and prevention of osteoporosis in postmenopausal women.
As outcomes for men who experience an osteoporotic fracture are poor, treatments that have been shown to improve bone mineral density (BMD) and decrease fractures in this patient population, such as a bisphosphonate (alendronate, risedronate or zoledronic acid) or denosumab, are recommended.
Fifty-three men treated with antiepileptic drugs for at least two years prior to enrollment in the Anti-Epileptic Drug and Osteoporosis Prevention Trial (ADOPT) were randomized to receive risedronate (a drug that helps prevent fractures) or a placebo for 12 weeks.
All enrolled participants received calcium and vitamin D supplementation, and were randomized to risedronate or matching placebo.
The guidelines also advocate medical therapy with zoledronic acid or other bisphosphonate drugs--alendronate (Fosamax), risedronate (Actonel), or deno-sumab (Prolia)--or teriparatide (Forteo) for men with a history of hip or spinal fracture and men at high risk of fracture based on DXA results and clinical risk factors.
Deux medicaments font reference, l'alendronate et le risedronate, sur lesquels nous disposons d'un recul de plus de 10 ans.
Risedronate and Zoledronate potently block isoprenoid biosynthesis, but are unable to get across the membrane of red blood cells to get to the parasite.