Two rotavirus vaccines are currently licensed globally: the monovalent Rotarix vaccine (RV1, GlaxoSmithKline; 2-dose series) and the pentavalent RotaTeq
vaccine (RV5, Merck; 3-dose series).
The results of the study conducted in 7,500 infants across 6 Indian sites demonstrated that Rotasiil's efficacy was comparable to the performance of the leading RotaTeq
and Rotarix brands in Bangladesh and in some African countries, according to the study published in the journal Vaccine.
The results demonstrated by ROTASIIL in India appear generally comparable to the performance of RotaTeq
and Rotarix in Bangladesh and in some African countries.
Mixing the RotaTeq
and Rotarix rotavirus vaccines schedules resulted in noninferior immunogenicity compared with using only one vaccine schedule, found a new multicenter, open-label study, said Dr.
In June 2013, the CDC published a study in the journal Pediatrics that analyzed the VAERS database to assess intussusception events in recipients of two rotavirus vaccines, RotaTeq
In 2006 and 2008, two live-attenuated vaccines, RotaTeq
(Merck, Whitehouse Station, NJ, USA) and Rotarix (GlaxoSmithKline, Rixensart, Belgium), respectively, were introduced in the United States (4).
Currently there are two live orally-administered Rotavirus vaccines: Rotarix and RotaTeq
The TGA, working in collaboration with state health authorities, has completed an investigation into the association between the use of the rotavirus vaccines Rotarix (GSK) and RotaTeq
(Merck/CSL) and the occurrence of a rare form of bowel obstruction known as intussusception (IS).
Rotavirus vaccines are currently available in oral drops of two or three doses, and costs from Dh255 per dose for Rotarix (two doses) and Dh273 per dose for RotaTeq
Major reduction of rotavirus gastroenteritis cases seen in hospital after introduction of RotaTeq
vaccine into National Immunization Program of Finland.
M2 EQUITYBITES-May 28, 2012-Merck's ROTATEQ
vaccine introduced by government of Rwanda(C)2012 M2 COMMUNICATIONS http://www.
The two rotavirus vaccines used in the US - Merck's (NYSE:MRK) RotaTeq
and GlaxoSmithKline's (LON:GSK) Rotarix - showed efficiency of between 85% and 98% in preventing severe rotavirus disease in clinical trials conducted in several developed countries, including the US.