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 (no͞o′klē-ās′, -āz′, nyo͞o′-)
Any of several enzymes, including the endonucleases and the exonucleases, that hydrolyze bonds between nucleotides in nucleic acids.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) any of a group of enzymes that hydrolyse nucleic acids to simple nucleotides
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈnu kliˌeɪs, -ˌeɪz, ˈnyu-)

any enzyme that catalyzes the hydrolysis of nucleic acids.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nuclease - general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units
endonuclease - a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes
exonuclease - a nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Plasmids carrying the vanA gene cluster were detected by using S1 nuclease digestion followed by hybridization with a vanA probe (4).
To eliminate psyllid RNA, RNAs were treated with S1 nuclease (Invitrogen).
Genetic location of the [bla.sub.NDM -] gene was determined by probing S1 nuclease pulsed-field gels.