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Noun1.SCNT - moving a cell nucleus and its genetic material from one cell to another
biological research - scientific research conducted by biologists
biomedical cloning, therapeutic cloning - nuclear transplantation of a patient's own cells to make an oocyte from which immune-compatible cells (especially stem cells) can be derived for transplant
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References in periodicals archive ?
Complement protein C3 knock-out piglets were generated using modification of fetal porcine fibroblasts via nucleofection with CRISPR/ Cas9 coding plasmid followed by SCNT. Out of 300 transferred reconstructed oocytes, 19 alive piglets with C3 knock-out were obtained (24).
Patient specific embryonic stem cells derived from human SCNT blastocysts.
Historically, primates have been resistant to SCNT because of the way their egg cells are structured.
A rhesus monkey called Tetra was the first primate to be cloned, in 1999, but that procedure - embryo splitting - was a simpler method than SCNT. Similar to how twins are born, that method can produce a maximum of four clones at a time.
We demonstrated that targeted cells could possibly be used as nuclear donors in SCNT and are capable of directing development to at least 90d of pregnancy by second round SCNT.
Our lab has used a unique cell line of shTNFRI-Fc and HO-1 pig for SCNT that have only 15 copies of the shTNFRI-Fc and HO-1 genes.
Peter Nygard practices and supports all paths to regenerative medicine and is best known for his SCNT work.
In 1997, Dolly the sheep came into this world through a process called Somatic Cell Nuclear Transfer (SCNT).
Position D allows the creation of human embryos specifically for research via both fertilization and somatic cell nuclear transfer (SCNT).
Recent techniques involving induced pluripotent stem cells (iPSCs) and human somatic cell nuclear transfer (SCNT) have raised new ethical and legal questions.