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Noun1.SCNT - moving a cell nucleus and its genetic material from one cell to another
biological research - scientific research conducted by biologists
biomedical cloning, therapeutic cloning - nuclear transplantation of a patient's own cells to make an oocyte from which immune-compatible cells (especially stem cells) can be derived for transplant
References in periodicals archive ?
com/cell/fulltext/S0092-8674(18)30057-6) open-access paper that appeared Thursday in the journal Cell, said the researchers tried a number of different ways to get SCNT to work with monkeys, and failed a number of times before finally succeeding.
We demonstrated that targeted cells could possibly be used as nuclear donors in SCNT and are capable of directing development to at least 90d of pregnancy by second round SCNT.
Professor Sinclair added: "Despite technological advances in recent years, efficiency of SCNT remains low but there are several groups across the world working on this problem at present and there is reason to be optimistic that there will be significant improvements in future.
SCNT is currently being performed in several laboratories worldwide for the purpose of creating human stem cells.
One attraction of SCNT has always been that the genetic identity of the new pluripotent cell would be the same as the patient's, since the transplanted nucleus carries the patient's DNA," said cardiothoracic surgeon Sonja Schrepfer.
The problem of abnormally large offspring was first described for calves born from blastomere NT procedures (6, 7) but was subsequently shown to occur in embryos produced by IVF (8, 9) and SCNT (10, 11, 12, 13) procedures.
The article quoted DeGette as saying, "I hope the NIH will allow SCNT [human cloning] to move forward with federal funding.
Having learnt some lessons from SCNT (cloning), we need to be very cautious in generating stem cells by directed differentiation (IPS) or de-differentiation for cell therapy to treat diseases.
Leaving aside the question of whether body parts and tissues should be bought and sold for any purpose, it's important to note that eggs used for reproduction will result in a baby at least some of the time, while benefits from SCNT research are unknown.
The General Assembly of the United Nations failed to reach agreement on a treaty regarding somatic cell nuclear transfer, also known as SCNT (Caulfield and von Tigerstrom 2005).
294), while SCNT (following McHugh) results in "an embryo-like entity that can form tissue but not organize a fetus .
The resulting restrictive statutory provisions that ban SCNT ultimately arose from a convergence of rhetoric on dignity and the moral status of the embryo, and the resultant promotion of adult stem cell research.