SNRI


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SNRI

 (ĕs′ĕn-är-ī′)
n.
Any of a class of drugs, such as duloxetine or venlafaxine, that inhibit the reuptake of the neurotransmitters serotonin and norepinephrine in the central nervous system and are used primarily in the treatment of depression.

[s(erotonin-)n(orepinephrine) r(euptake) i(nhibitor).]
References in periodicals archive ?
To study the association further, they analyzed four serotonin and norepinephrine reuptake inhibitors (SNRIs) and five NDMA receptor antagonists.
Overall, the investigators found 19,017 patients who were prescribed both triptans and an SSRI or SNRI.
For women with breast cancer who are taking an aromatase inhibitor, and who are also experiencing mood changes with their hot flashes, we often choose a trial of a low-dose antidepressant, either an SSRI or SNRI. One drug is approved by the US Food and Drug Administration (FDA) for the treatment of hot flashes (but not for mood disorder).
Food and Drug Administration issued an advisory warning on the risk of serotonin syndrome with concomitant use of triptans and SSRI or SNRI antidepressants, Yulia Orlova, M.D., Ph.D., from Brigham and Women's Hospital in Boston, and colleagues used electronic health record data to examine the risk of serotonin syndrome.
A 2015 meta-analysis that examined nine randomized controlled trials of SSRIs and serotonin and norepinephrine reuptake inhibitors (SNRIs) for pediatric anxiety disorders concluded that these agents provided a benefit of modest effect size.
In another study it was seen that adding L-Methylfolate to selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) when starting pharmacotherapy leads to greater reduction of depressive symptoms in a shorter time compared with SSRI or SNRI monotherapy8.According to the study the efficacy of L-Methylfolate and SSRI was 18.5% as compared to 7.04% efficacy of SSRI or SNRI monotherapy9 showing a difference in response of 11.5% Papakostas et all showed that adjunctive L-methylfolate at 15mg/day showed significantly greater efficacy compared with continued SSRI therapy plus placebo on both primary outcome measures (response rate and degree of change in depression symptom score) and two secondary outcome measures of symptom severity10.
First-line medication is a selective serotonin reuptake inhibitor (SSRI) or a serotonin-norepinephrine reuptake inhibitor (SNRI) due to the better tolerability and lower adverse effect profile of these classes compared with the tricyclic antidepressants or monoamine oxidase inhibitors.
The medication that most effectively kept patients from returning to the hospital was not a selective serotonin reuptake inhibitor (SSRI), a serotonin nor-epinephrine reuptake inhibitor (SNRI), or an atypical antipsychotic.
From inside the computer simulated grounds of Shapash Nuclear Research Institute (SNRI), delegates saw how specialists in training navigate through realistic scenarios to learn the ins and outs of nuclear security threats and risks.
SSRI: Serotonin reuptake inhibitors, SNRI: Serotonin noradrenaline reuptake inhibitors, TCA: Tricyclic antidepressants, AED: Antiepileptic drugs, GABA: Gamma amino butyric acid
The increased risk was associated with all of the most frequently used antidepressant groups, which were selective serotonin reuptake inhibitors (SSRI drugs), mirtazapine and selective noradrenaline reuptake inhibitors (SNRI drugs).