ALS

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Related to SOD1: SOD2, SOD3, G93A

ALS

abbr.
1. amyotrophic lateral sclerosis
2. autograph letters, signed
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ALS

abbreviation for
autograph letter signed
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ALS

amyotrophic lateral sclerosis.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ALS - thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cordALS - thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs
amyotrophic lateral sclerosis, Lou Gehrig's disease
nervous disorder, neurological disease, neurological disorder - a disorder of the nervous system
induration, sclerosis - any pathological hardening or thickening of tissue
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
It is estimated that 10% of all cases are thought to be inherited as a dominant trait, or otherwise known as Familial ALS (FALS.) Approximately 15 to 20 percent of FALS cases are caused by mutations in the gene that produces the copper zinc superoxide dismutase 1 (SOD1) enzyme, which leads to a progressive degeneration of motor neurons affecting movement and muscle control.
APB-102 RECEIVES ORPHAN DRUG DESIGNATION FROM FDA
In the same study, rosiglitazone also upregulated SOD1 and SOD2 expression and activity (Pei et al., 2013).
Pioglitazone Mediated Reduction in Oxidative Stress and Alteration in Level of PPARI3, NRF2 and Antioxidant Enzyme Genes in Mouse Preimplantation Embryo during Maternal to Zygotic Transition
SOD1 farelerde, spinal kilcal damarlarin in vivo iki-foton mikroskopta goruntulenmesi, kilcal damarlarin hem capinin hem de yogunlugunun azaldigini gostermistir (64).
Experimental Models in Neurodegenerative Diseases/ Norodejeneratif Hastaliklarda Deneysel Modeller
Gene expression changes in antioxidant genes showed that hGFC expressed NRF2 and SOD1 when treated or not with AFED at both concentrations.
In vitro evaluation of Eugenia dysenterica in primary culture of human gingival fibroblast cells
New insights on the mechanisms of disease course variability in ALS from mutant SOD1 mouse models.
Repetitive Nerve Stimulation in Amyotrophic Lateral Sclerosis
We used RT-PCR to determine the relative mRNA abundance of genes related to oxidative stress (NRF2, SOD1, CAT, and GPX4).
Effects of epigallocatechin-3-gallate on bovine oocytes matured in vitro
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
Role of non-coding RNAs in non-aging-related neurological disorders
The most common gene mutations related with FALS are C9orf72, SOD1, TDP43, FUS and ubiquilin 2 (UBQLN2).
Two Families with SOD1 (L144F) and C9orf72 Gene Mutations and an Overview of Amyotrophic Lateral Sclerosis/SOD1 (L144F) ve C9orf72 Gen Mutasyonlari Saptanan Iki Aile ve Amiyotrofik Lateral Skleroza Genel Bakis
When the SOD1 gene is mutated, the protein assembly process malfunctions and steps are missed out.
Old drug, new usage!
M2 EQUITYBITES-January 25, 2018-Orphazyme announces manuscript publication of phase II trial results for arimoclomol in patients with SOD1 ALS
Orphazyme announces manuscript publication of phase II trial results for arimoclomol in patients with SOD1 ALS
M2 PHARMA-January 25, 2018-Orphazyme announces manuscript publication of phase II trial results for arimoclomol in patients with SOD1 ALS
Orphazyme announces manuscript publication of phase II trial results for arimoclomol in patients with SOD1 ALS

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