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Any of a class of drugs, such as fluoxetine or sertraline, that inhibit the reuptake of serotonin by neurons of the central nervous system and are primarily used in the treatment of depression and obsessive compulsive disorder.
[s(elective) s(erotonin) r(euptake) i(nhibitor).]
(Pharmacology) selective serotonin reuptake inhibitor; any of a class of drugs, including fluvoxamine, paroxetine, fluoxetine (Prozac), and Lustral, that increase concentrations of serotonin in the brain: used in the treatment of depression
Selective Serotonin Reuptake Inhibitor: any of several drugs that inhibit the reabsorption of serotonin by nerve cells, leading to more serotonin activity in the brain: used chiefly as an antidepressant.
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|Noun||1.||SSRI - an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain|
antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects
fluoxetine, fluoxetine hydrocholoride, Prozac, Sarafem - a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain
paroxetime, Paxil - a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Paxil)