sandwich compound

(redirected from Sandwich complex)

sandwich compound

n
(Elements & Compounds) chem any of a class of organometallic compounds whose molecules have a metal atom or ion bound between two plane parallel organic rings. See also metallocene
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In this assay, a sandwich complex was formed using the beads and nanovesicles.
In the Elecsys intact PTH assay, a biotinylated anti-PTH monoclonal antibody and a ruthenium-labeled anti-PTH monoclonal antibody form a sandwich complex with PTH, after which streptavidin-coated microparticles are added to magnetically separate out the sandwich complex via biotin and streptavidin interaction.
The sample is incubated for 21 min at 37[degrees]C with both antibodies simultaneously, leading to the formation of a soluble sandwich complex in the presence of ACTH molecules.
The immunological reaction consists of a first incubation where 50 [micro]L of sample, the biotinylated antibody, and the Ru-labeled antibody react for 9 min, when antibodies capture the TSH present in the sample to form a sandwich complex. In a second step, streptavidin-coated paramagnetic microparticles are added, and during a second 9-min incubation time the biotinylated antibody attaches to the streptavidin-coated surface of the microparticles.