The active ingredient in Prozac is Fluoxetine, which is also sold under other brand names, such as Sarafem
Other ingredients found in the rock bass fish - and the other nine fish species - included citalopram (the active ingredient in Celexa) and norfluoxetine (the active ingredient in Prozac and Sarafem
Fluoxetine (Prozac, Sarafem
) and duloxetine (Cymbalta) have often been confused because of their similar sounding names.
Commonly prescribed SSRIs include fluoxetine (Prozac, Sarafem
), sertraline (Zoloft), paroxetine (Paxil), fluvoxamine (Luvox), citalopram (Celexa) and escitalopram oxalate (Lexapro).
Debate over PMDD intensified in 2000, when the Food and Drug Administration approved the rebranding of the selective serotonin reuptake inhibitor (SSRI) fluoxetine under the marketing name Sarafem
to treat PMDD.
Lilly's fluoxetine (Prozac) was approved under the trade name Sarafem
for premenstrual dysphoric disorder in 2000, Pfizer's sertraline (Zoloft) added the PMDD claim in 2001, and GlaxoSmithKline's paroxetine (Paxil CR) followed in 2003.
Davi Johnson (2004) similarly found that advertisements for Sarafem
, a psychiatric medication for treating premenstrual dysphoric disorder (PMDD), are designed to simulate an intimate interpersonal encounter when featuring testimonials from a variety of women (p.
Paroxetine was the most commonly used SSRI in this study (25.9%), followed by sertraline (Zoloft, 22.3%), citalopram (Celexa, 19.2%), venlafaxine (Effexor, 15.0%), fluoxetine (Prozac, Sarafem
, 10.4%), and fluvoxamine (Luvox, 7.2%).
Anti-psychotics such as Zyprexa from Eli Lilly and Seroquel ($3.8 billion in sales in 2008) may not yet be the household names that Prozac, Ritalin, Paxil, Zoloft and Sarafem
are, but still are mega-blockbusters, a blockbuster being the code word for a drug that pulls in more than a billion in sales.
"Brittany took (painkiller) Vicoprofen and (PMT drug) Sarafem
five days a week before her period.
In fact, a few studies found that 30 milligrams of saffron was just as effective as commonly prescribed fluoxetine (Prozac, Sarafem
) and imipramine (Tofranil) for treating mild-to-moderate depression.
Some of products expected to come off patent in 2008 include Sarafem
for premenstrual dysphoric disorder, Depakote for seizures, Cipro HC for external ear infections, and Dovonex for psoriasis.