The conventional outflow pathway, consisting of the trabecular meshwork and a specialized vessel called Schlemm's canal
, controls IOP and has been identified as the site of increased resistance to aqueous humor outflow in POAG.
The presence of fibronectin, an extracellular glycoprotein in the trabecular tissue, mainly, in the inner wall of schlemm's canal
and juxtacanalicular, or cribriform part of trabecular meshwork has been verified by other workers also.7 Glucose concentration is believed to be higher in aqueous humor of diabetic patients.
Roughly the size of an eyelash, the Hydrus Microstent is a next-generation MIGS device designed to reduce eye pressure by reestablishing flow through Schlemm's canal
, the eye's natural outflow pathway.
Anterior segment dysgenesis occurs when the structures of the anterior segment of the eye are affected, such as the cornea, iris and lens, anterior chamber and posterior chamber, trabecular meshwork, and Schlemm's canal
The laser dissection of the deep sclera and Schlemm's canal
towards the trabeculo-Descemet's membrane was performed to achieve aqueous humour percolation (Figure 5(c)).
In PC, 360[degrees] of Schlemm's canal
circumference was catheterized and viscodilated with prolene suture left under tension to distend the trabecular meshwork inward.
They discuss trabeculectomy, deep sclerectomy, glaucoma drainage device surgery, postoperative management of filtering procedures, the role of the ocular surface, and modulation of scarring processes in glaucoma surgery; new devices and techniques, including laser-assisted techniques, viscocanalostomy and canaloplasty, and ab interno Schlemm's canal
surgery; and surgical approaches to angle-closure glaucoma, concomitant cataract and glaucoma, pediatric glaucoma, and refractory glaucoma.
By promoting autophagy, it may prevent exfoliated cells from blocking the aqueous humor drainage channels of the meshwork and the Schlemm's canal
In the transition zone between the gray and white limbus was the scleral sulcus containing Schlemm's canal
. A 1 mm radial incision was made, entering Schlemm's canal
externally, and the incision was slowly deepened until the outer wall of Schlemm's canal
was opened and a sleeping aqueous humor was seen.
Glauko's iStent improves outflow by creating a patent bypass between the anterior chamber and Schlemm's canal
. It sells products through a network of distributors in Portugal, Germany, Italy, Canada, Spain, the UK and France.
The Hydrus creates a large opening through the traditional source of flow blockage (known as the trabecular meshwork) and it dilates and scaffolds the conventional pathway (known as Schlemm's canal
) through which fluid exits the eye.
This implant may also be used in deep sclerectomy to simplify the difficult dissection of Schlemm's canal
and Trabeculo-Descemet's membrane.