sickle-cell disease

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Noun1.sickle-cell disease - a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
anemia, anaemia - a deficiency of red blood cells
References in periodicals archive ?
Sickle-cell anaemia is an inherited condition caused by an abnormal form of haemoglobin in the blood and is more common in people of African descent.
The pain was caused by Haywood's sickle-cell disease, a genetic condition in which misshapen red blood cells build up in the blood vessels and cause infections, strokes, and excruciating episodes of pain.
Decreased RBC's elasticity is central to the pathophysiology of sickle-cell disease.
Sickle-cell disease is a hereditary blood disorder that affects red blood cells which can lead to life-threatening complications and a life expectancy of 20-30 years less than those that are not affected.
Osteomyelitis in patients who have sickle-cell disease.
Over the years, there have been case reports of sudden death during physical exertion in young adults with sickle-cell disease.
Roughly one-third of adults with sickle-cell disease develop increased blood pressure in the lungs.
Why are the experts so wrong about the prognosis (that is the survival outlook), of the person with sickle-cell disease (Ache/Ache)?
He altered its genes (chemical instructions that, influence how certain characteristics develop) so the rodent would carry human sickle-cell disease.
The factory churns out Nicosan, the first non-toxic treatment for sickle-cell anemia, a disease that afflicts about 16 million individuals primarily of African descent worldwide.
A protein found on red blood cells in sickle-cell disease binds these cells to blood vessel walls, disrupting circulation, a new study suggests.