SV40

(redirected from Simian vacuolating virus 40)
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SV40

 (ĕs′vē-fôr′tē)
n.
A polyomavirus found in humans and other mammals that causes tumors in certain species, such as hamsters and rats, and various diseases in immunocompromised monkeys. It has been widely researched as a model of viral replication and gene expression and a possible cause of certain cancers in humans.

[s(imian) v(irus) 40.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
There have been a number of well-documented instances of contaminated vaccines transmitting viruses to humans, such as batches of poliovirus and adenovirus vaccines that were found to be contaminated with Simian vacuolating virus 40 (SV40) from rhesus monkey kidney cells in the late 1950s and early 1960s; and some early batches of yellow fever vaccine produced in hens' eggs were found to be contaminated with avian leucosis virus.
Efficient establishment of pig embryonic fibroblast cell lines with conditional expression of the simian vacuolating virus 40 large T fragment.