SV40

(redirected from Simian virus 40)
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Related to Simian virus 40: adenovirus

SV40

 (ĕs′vē-fôr′tē)
n.
A polyomavirus found in humans and other mammals that causes tumors in certain species, such as hamsters and rats, and various diseases in immunocompromised monkeys. It has been widely researched as a model of viral replication and gene expression and a possible cause of certain cancers in humans.

[s(imian) v(irus) 40.]
References in periodicals archive ?
Abbreviations BKPyV: BK polyomavirus JCPyV: JC polyomavirus PVAN: Polyomavirus-associated nephropathy PML: Progressive multifocal leukoencephalopathy PML-IRIS: Progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome VLP: Virus-like particle SV40: Simian virus 40 LT: Large T antigen PBS: Phosphate-buffered saline CCK-8: Cell Counting Kit 8 HAU: Hemagglutination unit.
Kennedy, "Immunization of BALB/c mice with recombinant simian virus 40 large tumor antigen induces antibody-dependent cell-mediated cytotoxicity against simian virus 40-transformed cells: an antibody-based mechanism for tumor immunity," Journal of Immunology, vol.
Enumeration of the simian virus 40 early region elements necessary for human cell transformation.
Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts.
BK virus, JC virus, and simian virus 40 infection in humans, and association with human tumors.
The UROtsa cell line was derived from normal human urothelium lining the ureter and was immortalized using simian virus 40 (SV40) large T-antigen (Petzoldt et al.
Simian virus 40) which have shown to cause unique cancers in some people.
Researchers examined nearly 400 tumors and control tissues and found the viral footprint for simian virus 40 (SV40) in the tumors of 43 percent of patients with non-Hodgkin lymphoma.
The "footprint" of simian virus 40 (SV40) was found in 43percent of the non-Hodgkin's samples.
Lednicky, "Cell and Molecular Biology of Simian Virus 40: Implications for Human Infections and Disease," Journal of the National Cancer Institute, 91: 2(1999): 119-134.
The once hailed 'miracle' vaccine was contaminated by a virus called Simian Virus 40 (SV40) between the years of 1955 and 1963.