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Related to Somatomedins: Somatomedin C, Enamel lamellae


 (sō-măt′ə-mēd′n, sō′mə-tə-)
[Perhaps somato(tropin) + (inter)med(iary) + -in.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) a protein hormone that promotes tissue growth under the influence of growth hormone
[C20: from somato- + Latin medius middle + -in]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(səˌmæt əˈmid n)

any of various liver hormones that enhance the activity of a variety of other hormones, as somatotropin.
[1970–75; somato- + -med-, as in intermediary]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
Here is increased availability of cross bridges for generating force of muscle contraction by somatomedins mediated increase in actin- and myosin-like contractile protein formation.
They added that several factors related to the person's state of nutrition or stress are known to stimulate secretion: starvation, hypoglycemia exercise, excitement and trauma, also it has been found that growth hormone causes the liver and other tissues as muscles to form several small proteins called somatomedins, many of the somatomedin effect on growth are similar to the effects of insulin on growth, they are called insulin like growth factor.
Salmon and Daughaday first hypothesized the existence of the IGFs back in 1957 as they searched for growth hormone (GH) mediators, initially naming the two IGFs "somatomedins A and C." (2,3)
GH realizes its peripheral effects indirectly through somatomedins, predominantly IGF-I (22) which is produced mainly by the liver and to a lesser extent by peripheral tissues (27).