What kind of spectacle would its hidden hemisphere present to our terrestrial spheroid
? Granting that the question at present was simply that of sending a projectile up to the moon, every one must see that that involved the commencement of a series of experiments.
He thus obtained a spheroid
, the capacity of which amounted, in round numbers, to ninety thousand cubic feet.
At that precise moment we shall leave our spheroid
. Thus we still have twenty-seven minutes to remain on the earth."
Thus, to examine whether low-dose BPA would have the same proliferative effect on ER[alpha]-negative breast cells in a more tissue-like microenvironment, MCF10A cells were grown in an ECM gel in 3D spheroids
. The size of spheroids
was measured to determine whether the cells treated with low-dose BPA grew faster than the cells treated with ethanol (controls).
Sergiu Pasca of Stanford University and colleagues have developed what they call "human cortical spheroids
"The cortex spheroids
grow to a state in which they express functional connectivity, allowing for modelling and understanding of mental illnesses," said Thomas R Insel, Director of the National Institute of Mental Health.
In the past, the operator had been involved in the manufacture of coated propranolol spheroids
. The job involved a multi-stage batch process including mixing propranolol powder with various excipients followed by extrusion and spheronisation.
The comparison with the numerical results presented in [4, 5] show that for the sphere with k[rho] = 10 the accuracy of the asymptotic formulas is about 15-20% and for prolate spheroids
the accuracy of the asymptotics is much lower.
Scientists working on cancer research are now able to use a new non-adherent cell culture surface from Thermo Fisher Scientific, Waltham, Mass., to support the formation of consistent cancer spheroids
in vitro, simulating the 3-D structures of tumor growth and providing a better model system for studying tumor cell progression and the efficacy of anticancer agents than 2-D systems and other surfaces.
Cells of these spheroids
demonstrate increased production and cell function more closely aligned to that of in vivo hepatocytes compared to cells comprising a traditional monolayer morphology .
This study compared the antiproliferation activity of DC extract alone, and in combination with chemotherapeutic agents gemcitabine (GEM), cisplatin (CDDP), and paclitaxel (PTX) on human pancreatic cancer PANC-1 3D spheroids
and 2D monolayer cells.
Cells sediment spontaneously into the microcavities where they form spontaenously spheroids
within 24-48 hours.