spironolactone

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spi·ro·no·lac·tone

 (spī′rə-nō-lăk′tōn, spī-rō′-, spī-rŏn′ə-)
n.
An aldosterone antagonist and antiandrogen, C24H32O4S, that promotes diuresis and is used to treat fluid retention, androgenic syndromes in women, and hypertension.

[Alteration of spirolactone : Latin spīra, coil; see spiral + lactone.]

spironolactone

(ˌspaɪrənəʊˈlæktəʊn)
n
(Pharmacology) a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure
[C20: from spiro-2 + linking syllable -no- + lactone]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.spironolactone - a synthetic corticosteroid (trade name Aldactone) used to treat hypertensionspironolactone - a synthetic corticosteroid (trade name Aldactone) used to treat hypertension
antihypertensive, antihypertensive drug - a drug that reduces high blood pressure
adrenal cortical steroid, corticoid, corticosteroid - a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response; "adrenal cortical steroids are used to treat many different conditions"
Translations

spironolactone

n espironolactona
References in periodicals archive ?
Drugs selected for analysis Warfarin Methyldopa Gentamicin Lithium Hydrochlorthiazide Fluconazole Digoxin Zolpidem Ethinylestradil- Levonorgestrel Methotrexate Valsartan Paracetamol Carbamazepine Amiodarone Aminophylline Warfarin Atorvastatin Diclofenac Lithium Clarithromycin Spironolacton Digoxin Verapamil Furosemide Methotrexate Bisoprolol Indapamide Carbamazepine Glimepiride Alprazolam Warfarin Ciprofloxacin Lithium Amlodipine Digoxin Insulin Methotrexate Fluoxetine Carbamazepine Ramipril TABLE 2.
25 mg/d, aspirin 150 mg/d, furosemid 20 mg/d and spironolacton 50 mg/d) and he is currently being evaluated for heart and lung transplantation.