To study spore formation
in the laboratory, special sporulation media are often used .
The drug in question, cadazolid, is a novel quinoxolidinone antibiotic that has demonstrated efficacy as a strong inhibitor of Clostridium difficile protein synthesis, which results in the suppression of toxin production and spore formation
Microbiologists summarize the current understanding of bacterial spores, integrating several decades of research about the process of spore formation
in the model organism </B.
The persistence of infection might be explained by a questionable initial antimicrobial drug regimen but also by spore formation
and/or poor diffusion of antimicrobial drugs, as suggested by the presence of necrotic tissues such as the bone sequestrum.
It also indicates that we need to significantly improve our understanding of the factors that impact spore formation
and dispersion in order to efficiently manage plant diseases.