squalene


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squa·lene

 (skwā′lēn′)
n.
An unsaturated aliphatic hydrocarbon, C30H50, that is the biosynthetic acyclic precursor to tetracyclic steroids such as cholesterol. It is widely found in animals, plants, and fungi and is present in high concentrations in shark liver oil and human sebum.

[New Latin Squalus, shark genus (from its occurrence in the liver oil of sharks) (from Latin squalus, a sea fish) + -ene.]

squalene

(ˈskweɪˌliːn)
n
(Biochemistry) biochem a terpene first found in the liver of sharks but also present in the livers of most higher animals: an important precursor of cholesterol
[C20: from New Latin squalus genus name of the shark]

squa•lene

(ˈskweɪ lin)

n.
an oil, C30H50, intermediate in the synthesis of cholesterol, obtained for use in manufacturing pharmaceuticals.
[1925–30; < New Latin Squal(us) a genus of sharks (the liver of which yields the oil), Latin: a kind of fish + -ene]
References in periodicals archive ?
These authors showed that some gallates are potent inhibitors of the enzyme squalene epoxidase, which is involved in the biosynthesis of ergosterol [42] and, therefore, is essential for the survival of the microorganism.
Therefore, the present study was designed to investigate the expression of key enzymes of mevalonate pathway in (1) aortas from streptozotocin- (STZ-) induced 0-, 8-, and 16-week diabetic mice in vivo and (2) high-glucose-induced proliferated VSMCs in vitro, including HMGR, FPPS, FNT-[beta], GGT-1[beta], squalene synthase (SQS), phosphor-3-hydroxy-3-methylglutaryl- coenzyme A reductase (P-HMGR), and geranylgeranyl pyrophosphate synthase (GGPPS) (Figure 1).
Inhibition of squalene epoxidase by allylamines results in sterol deficiency in the fungal cell wall and also intracellular accumulation of squalene and finally fungal cell death.11 In one in vitro study terbinafine showed a weak effect against Malassezia furfur.12
Squalene is a major component of human skin lipid and is the single most abundant ozone-reactive constituent (Nicolaides, 1974).
ISO tensile bars were soaked in olive oil, squalene, and sun screen and oleic acid for five days at room temperature.
Organic (major) Triglycerides 30-40% Free fatty acids 15-25% Saturated 50% Monounsaturated 48% Polyunsaturated 2% Wax esters 20-25% Squalene 10-12% Cholesterol 1-3% Cholesterol esters 2-3% eRACE Activity on Commercial Phone Screen Protectors Buffer 0.00 Control w/o eRace -0.90 Supplier E sample B 15.10 Supplier E sample E 17.95 Supplier E sample F 18.33 Supplier E sample I 19.63 Supplier E sample 2B 9.60 Supplier E sample 2F 19.67 Supplier Z 15.20 Note: Table made from bar graph.
The human surface reaction with ozone was then improved by modeling the reaction with squalene. Next, the model was enhanced to include a computer-simulated person (CSP), a personal ventilation (PV) system, desk, floor diffuser and exhaust.
guajava leaf extract also contains squalene, which is commonly used in the cosmetic industry due to its antifungal properties [15, 16].
Squalene is also a compound commonly found in vegetable oils, particularly high in olive oils, with antioxidant property.
Vaginal lubricant and shark liver oil both contain an organic compound called squalene. This is often added to skin creams and moisturisers.
Olive powder contains high amounts of healthy compounds, including oleic acid, polyphenols, tocopherols, chlorophylls and squalene, which are beneficial for human health.
She was at Hay on Thursday to talk about the use of squalene, a substance found in sharks and used in the cosmetics industry.