To determine the causes and treatment outcome of Stevens-Johnson syndrome
(SJS) and toxic epidermal necrolysis (TEN).
(SJS) is a rare and acute life-threatening condition which is almost always precipitated by drugs.
CHICAGO -- Pediatric patients with Stevens-Johnson syndrome
and toxic epidermal necrolysis who received purely supportive care and surgical debridement had poorer outcomes, compared with other treatment modalities, a systematic review suggested.
Background: Stevens-Johnson syndrome
(SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases with high mortality rates.
The differential diagnosis include, Stevens-Johnson Syndrome
(SJS), Toxic Epidermal Necrolysis (TEN) or drug-induced pemphigus foliaceus.
This includes cases of Stevens-Johnson syndrome
, hypersensitivity reaction, and toxic epidermal necrolysis.
Although Stevens-Johnson syndrome
mostly appears as a reaction to some medicines, it has been separated from the erythema multiform spectrum and added to toxic epidermal necrolysis (3).
Material and Methods: Eleven patients diagnosed as Stevens-Johnson syndrome
, toxic epidermal necrolysis and Stevens-Johnson syndrome
/toxic epidermal necrolysis overlap in Department of Pediatric Allergy in Uludag University School of Medicine were included in this study.
De Guzman works with his residual vision, his eyes having been permanently damaged by Stevens-Johnson syndrome
, ultimately influencing how he perceives art and the world.
(SJS), also known as erythema multiforme major, is assumed to symbolize a range of infections, the most benign type of which is erythema multiforme (EM), whereas toxic epidermal necrolysis (TEN) is the most severe.
Immunohistochemical expression of apoptotic markers in drug-induced Erythema Multiforme, Stevens-Johnson Syndrome
and toxic epidermal necrolysis.
Doctors at the Royal Hospital for Sick Children in Edinburgh diagnosed Stevens-Johnson Syndrome
where the body's immune system overreacts to a trigger - usually a mild infection or medicine.