Every additional year of treatment with the listed antiretrovirals raised chances that HDL cholesterol would rise from low to normal levels, by the percentages shown: Sustiva (also Stocrin
, efavirenz), Viramune (nevirapine), Epzicom (also Kivexa, Ziagen [abacavir] plus Epivir [lamivudine]),Combivir (Retrovir [zidovudine] plus Epivir [lamivudine]), Trizivir (Ziagen plus Retrovir plus Epivir), Truvada (Viread [tenofovir] plus Emtriva [emtricitabine]), Kaletra (lopinavir plus ritonavir), Prezista (darunavir), Reyataz (atazanavir), and Isentress (raltegravir).
Em maio de 2007, pela primeira vez o pais levou a cabo o licenciamento compulsorio de uma droga -- o efavirenz, produzido pelo laboratorio Merck Sharp & Dohme e comercializado sob o nome de Stocrin
Merck Sharp and Dohme (MSD, who market efavirenz as Stocrin
in South Africa and many other parts of the world) provides prescriber information for efavirenz that cautions against conception in patients already on efavirenz as opposed to the prescription of efavirenz in women already known to be pregnant, in line with the WHO and BHIVA recommendations focusing on very early gestational risk.
In its successful blend of education, treatment advocacy and celebration of Zulu culture, the docu mirrors the Zulus' own methods of spreading the word: Choruses ask in song if the virus has arrived and intone the virtues of Stocrin
, Stavir 30 and condoms, while traditional healers prepare symptom-specific remedies in two-liter bottles.
In November 2006, Thailand issued a compulsory license on an important, newer ARV, efavirenz, sold by Merck under the brand-name Stocrin
African Comprehensive HIV/AIDS Partnership: Partnering with the Gates Foundation in Botswana, Merck commits US$50 million and continues donations of the antivirals Cirxivan and Stocrin
for the duration of the partnership.
Efavirenz (Sustiva, brand name Stocrin
in many countries)
Two anti-HIV medications -- Crixivan and Stocrin
-- are being provided for a discount of 85% to patients in Haiti, Trinidad & Tobago, the Dominican Republic, Guyana and Suriname, said Merck & Co.
cost is $5,000/patient/year) and Stocrin
available for $500/year for developing nations (New York Times, March 8, 2001, p.
Elsewhere, Merck markets the product, known by its generic name of efavirenz, under the Stocrin
Atazanavir, an experimental protease inhibitor being developed by Bristol-Myers Squibb, was compared in a large international trial with efavirenz (brand name Sustiva--or Stocrin
in some countries);
Trisivir: ZDV + 3TC + ABC) Non-nucleoside reverse transcriptase inhibitors (NNRTIs) Efavirenz (EFV, Low-fat meals improve Can be taken without Stocrin
, Sustiva) tolerability: high-fat regard to meals.