Spontaneous pneumothorax occurring in the majority of these patients arises from the rupture of subpleural
Focal consolidation, pleural effusion, subpleural
nodules, and cavitation were considered atypical findings.
and interstitial cysts were pale white to yellow, firm to the touch, and ruptured easily during handling.
The distribution of the process appeared to be random, with intra-alveolar hemorrhage seen in subpleural
, intralobular, paraseptal, and peribronchiolar locations.
UIP and NSIP patterns on HRCT scan (1-3) UIP NSIP Bilateral reticular opacities Bilateral reticular opacities Ground-glass opacities not Bilateral ground-glass prominent opacities Basal and subpleural
Basal predominance, diffuse or predominance subpleural
Fibrosis and honeycombing Honeycombing minimal or absent With or without traction With or without traction bronchiectasis bronchiectasis UIP = usual interstitial pneumonia; NSIP = nonspecific interstitial pneumonia; HRCT = high-resolution computerised tomography.
Inhaled carbon nanotubes reach the subpleural
tissue in mice.
A UIP pattern on HRCT, which may be sufficient for the diagnosis, relies on four criteria: subpleural
basal predominance; reticular abnormality; honeycombing.
Prominent interlobular septa, ground-glass attenuation, patchy consolidation, parenchymal bands, irregular peribronchovascular thickening, and subpleural
lines may be the initial findings on HRCT (14).
Contrast-enhanced chest computed tomography (CT) demonstrated extensive subpleural
honeycombing, consistent with pulmonary fibrosis (Figures 2 and3).
CT scans of the thorax, abdomen, and pelvis showed small subpleural
nodules in both lungs and jejunal wall thickening.
The left thyroid lobe was enlarged, with millimetric calcifications and, millimetric subpleural
pulmonary nodules and pleural fluid collection were identified by chest CT.
nodules, cavitary lesions few in number and a wedge shaped pleural based consolidation in the lateral segment of the right lung lower lobe were observed.