In patients with absence seizures (petit mal) who have failed to respond to succinimides
, clonazepam orally disintegrating tablets may be useful.
and Barker, J., "Understanding Polyisobutylene Succinimides
(PIBSI) and Internal Diesel Injector Deposits," SAE Technical Paper 2013-01-2682, 2013, doi: 10.4271/2013-01-2682.
"The electronic influence on the active site-directed inhibition of acetylcholinesterase by N-aryl-substituted succinimides
," Journal of the Mexican Chemical Society, vol.
Several investigators have synthesized AChE inhibitors like alkylpyridium polymers , dehydroevodiamine (DHED) , N-arylsubstituted succinimides
, lycorine derivatives , salicylanilide N-alkylcarbamates , and 7-methoxytacrineadamantylamine heterodimers .
In contrast, first-generation AEDs that do not appear to be associated with a significant risk of birth defects include the benzodiazepines (clonazepam [Klonopin], clorazepate [Tranxene], diazepam [Valium], and lorazepam [Ativan]) and succinimides
(ethosuximide [Zarontin] and methsuximide [Celontin]).
Polyether amines, polyisobutylene amines, and polyisobutylene succinimides
as fuel additives reduce the intake valve deposit by 45-60% from the base fuel and lower somewhat the combustion chamber deposit when compared to the base fuel.