sulfonylureas


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Related to sulfonylureas: Thiazolidinediones

sulfonylureas

These reduce the levels of glucose in the blood and are used to treat diabetes mellitus.
References in periodicals archive ?
are taking other medicines to treat diabetes, including insulin or sulfonylureas.
STOCKHOLM -- Sulfonylureas seem to substantially increase the risk for cardiovascular events relative to other antihyperglycemic agents, although they are effective glucose-lowering agents, according to several presentations given at the annual meeting of the European Association for the Study of Diabetes.
Sulfonylureas and glinides were discontinued at randomisation.
The study included 78,241 diabetics treated with metformin and 12,222 prescribed sulfonylureas, matched with 90,463 nondiabetic control subjects.
TEHRAN (FNA)- Patients diagnosed with diabetes and initially prescribed metformin to lower their glucose levels were less likely to require treatment intensification with a second oral medicine or insulin than patients treated first with sulfonylureas, thiazolidinediones or dipeptidyl peptidase 4 inhibitors, according to a study.
Neither sulfonylureas nor insulin was associated with a significant reduction in risk.
The drugs, glipizide, glyburide, and glimepiride, are known as sulfonylureas, which help decrease blood-sugar levels among type 2 diabetes patients by stimulating the pancreas to produce insulin.
The first-generation sulfonylureas currently available are chlorpropamide (Di-abinese), tolazamide (Tolinase), and tolbutamide (Orinase).
Pioglitazone (Actos) and rosiglitazone (Avandia), both TZDs, are approved for use in combination with metformin, sulfonylureas, glinides and insulin.
Akesis is developing proprietary products designed to lower and control blood glucose levels in patients with type 2 diabetes and holds numerous issued patents and patent applications relating to the use of chromium, vanadium and other components with sulfonylureas and other classes of diabetic agents.
Currently, the first-line oral agents for type 2 diabetes are metformin and sulfonylureas.