mastocytosis

(redirected from Systemic mastocytosis)
Also found in: Medical, Encyclopedia.
Translations

mas·to·cy·to·sis

n. mastocitosis, mastocitos neoplásicos que aparecen en varios tejidos como urticaria pigmentosa.

mastocytosis

n mastocitosis f
References in periodicals archive ?
Blueprint Medicines is initially developing avapritinib for the treatment of advanced GIST, advanced systemic mastocytosis (SM), and indolent and smoldering SM.
kinase switch control inhibitor in clinical development for the treatment of KIT and/or PDGFR?-driven cancers, including gastrointestinal stromal tumors, or GIST, systemic mastocytosis, or SM, and other cancers.
Serum tryptase levels > 20 ng/mL have been shown to correlate with a higher probability of systemic mastocytosis. Higher tryptase levels also correlate with severity of disease in children.
Blueprint Medicines announced updated data from the ongoing, registration-enabling EXPLORER trial of avapritinib in patients with systemic mastocytosis. The updated data showed a confirmed overall response rate of 77% in advanced SM patients, as assessed by a central review committee of SM clinical experts.
This single centre, first-in-human Phase 1 clinical trial of GTB-3550 will enrol up to 60 subjects with CD33-expressing high risk for refractory/relapsed AML, MDS, or advanced systemic mastocytosis. Subjects will receive a single course of GTB-3550 TriKE given as three weekly treatment blocks.
Two weeks before her wedding in November 2017 she was diagnosed with systemic mastocytosis; this has made life particularly difficult, as her immune system is now so low it means a cough or cold could be enough to kill her.
Special laboratory test were recommended to be left to bone disease specialist including bone turnover markers, a serum tryptase /urine, N-methylhistamine to screen for systemic mastocytosis, antitransglutaminase antibodies for celiac disease, a 24-hour urinary free cortisol and/or overnight dexamethasone suppression test to identify patients with Cushing syndrome and bone biopsy.
Systemic mastocytosis (SM) [6] is a hematologic neoplasm characterized by an accumulation of clonal mast cells in the bone marrow (BM) and other extracutaneous organs (1).
Rolly, "Anaesthetic management of systemic mastocytosis," British Journal of Anaesthesia, vol.
West recommended that are best left to bone disease specialists include bone turnover markers, a serum tryptase / urine N-methylhistamine to screen for systemic mastocytosis, antitransglutaminase antibodies for celiac disease, a 24-hour urinary free Cortisol and/or overnight dexamethasone suppression test to identify patients with Cushing syndrome, and bone biopsy.
Blood cell count was within normal values, which is in accordance with cutaneous mastocytosis; in systemic mastocytosis, blood cell counts may reveal anemia, thrombocytopenia, thrombocytosis, leukocytosis, and eosinophilia.
Full browser ?