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Related to Systemic scleroderma: systemic lupus erythematosus


A pathological thickening and hardening of the skin.


(ˌsklɪərəʊˈdɜːmə) ,




(Pathology) a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin
[C19: from New Latin sclerōdermus, from Greek, from sklēros hard + derma skin]


(ˌsklɪər əˈdɜr mə, ˌsklɛr-)

a disease in which connective tissued becomes hardened and rigid.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.scleroderma - an autoimmune disease that affects the blood vessels and connective tissuescleroderma - an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin
autoimmune disease, autoimmune disorder - any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues
morphea - localized scleroderma
2.Scleroderma - genus of poisonous fungi having hard-skinned fruiting bodies: false truffles
fungus genus - includes lichen genera
family Sclerodermataceae, Sclerodermataceae - a family of fungi or order Sclerodermatales with a single-layered peridium; includes earthballs
earthball, hard-skinned puffball, puffball, false truffle - any of various fungi of the genus Scleroderma having hard-skinned subterranean fruiting bodies resembling truffles
Scleroderma aurantium, Scleroderma citrinum - an earthball fungus that is a dingy brownish yellow and a dark purplish interior; the peridium is covered with a pattern of small warts
Scleroderma flavidium, star earthball - an earthball with a smooth upper surface that is at first buried in sand; the top of the fruiting body opens up to form segments like the ray of an umbel
Scleroderma bovista, smooth earthball - an earthball with a peridium that is firm dry and smooth when young but developing cracks when mature; pale orange-yellow when young and reddish brown at maturity


n. escleroderma, esclerodermia, induración y casi total atrofia de la epidermis.


n esclerodermia, esclerosis sistémica progresiva; localized — esclerodermia localizada
References in periodicals archive ?
ENPNewswire-August 27, 2019--Emerald Health Pharmaceuticals Completes First-In-Human Clinical Study of Novel Oral Treatment for Multiple Sclerosis and Systemic Scleroderma
Emerald Health Pharmaceuticals and Lonza have entered an agreement for the large-scale manufacturing of a new synthetic derivative of cannabidiol (CBD) and its oral drug product for the treatment of multiple sclerosis (MS) and systemic scleroderma, also known as systemic sclerosis (SSc).
(20) could not demonstrate improvement in flow in the Doppler study after treatment with botulinum toxin in patients with Raynaud's phenomenon secondary to systemic scleroderma (20).
Contract notice: medicinal products for the treatment of pulmonary arterial hypertension and systemic scleroderma
Bergman et al., "Double-blind, placebo-controlled study of oral calcitriol for the treatment of localized and systemic scleroderma," Journal of the American Academy of Dermatology, vol.
Pterygium inversum is usually seen in systemic scleroderma and with systemic lupus erythematosus.
There are two main types of the disease: the localized form (called localized scleroderma, limited scleroderma, or morphea) and the systemic form (called systemic scleroderma, diffuse scleroderma, generalized scleroderma, or systemic sclerosis).
There are, unquestionably, risks with transplant, but the SCOT findings support myeloablative autologous HSCT as a significant advance in the care of diffuse cutaneous systemic scleroderma with internal organ involvement, as this approach provided superior long-term outcomes, compared with 12 months of IV cyclophosphamide, he said, adding that the global rank composite score developed for this study was a useful measure of scleroderma outcomes.
Comparison of a new, modified lung ultrasonography technique with high-resolution CT in the diagnosis of the alveolo-interstitial syndrome of systemic scleroderma. Med Ultrason 2014;16:27-31.
Her form of systemic scleroderma can also affect the internal organs, including the heart, kidneys and bowel.
Cardiovascular assessment of asymptomatic patients with juvenile-onset localized and systemic scleroderma: 10 years prospective observation.