helper T cell

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helper T cell

Any of a class of T cells that are activated by interacting with antigen-presenting cells, such as a dendritic cells, and then function to activate other cells of the immune system, including B cells, cytotoxic T lymphocytes, and phagocytes. Activated helper T cells usually have CD4 receptors on the surface. Also called T-helper cell.

helper T cell

any of a group of T cells that activate the immune system either by enhancing the production of antibody and other T cells or by mobilizing macrophages to engulf invading particles.

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Noun

helper T cell - T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus

CD4 cell, CD4 T cell, helper cell

T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells

References in periodicals archive ?

However, the PHI group did exhibit stronger T helper cell responses, which led the researchers to suggest that "individuals treated in early infection may benefit from [therapeutic] strategies aimed at enhancing virus-specific CTL responses, whereas individuals treated later in infection may benefit from strategies aimed at enhancing HIV-1-specific T helper cell functions as well as broadening CTL responses to combat increased viral diversity.

Can treatment during primary HIV infection lead to control of disease without drugs?

The study demonstrates that MUC-1 in the form of an immune complex is more efficiently processed than MUC-1 alone, leading to T helper cell stimulation and an enhanced cytotoxic T lymphocyte (CTL) response.

ViRexx Partner Presents at Annual Conference of The American Association of Cancer Research

Our findings, in both animal and human models, indicate that the type of T helper cell present is the determining factor in predicting whether interferon-_ will be effective," Raman added.

First biomarker for multiple sclerosis found

By understanding the role Stat4 plays in IL-12 signaling and T helper cell differentiation, we have achieved the first steps in a new approach to treating immune-mediated diseases," said David V.

Researchers at Harvard University and Tularik Inc. Report Stat4 Gene Regulation Controls Immune System Response

To our knowledge, this is the first transcription factor that appears to regulate this switching of T helper cell phenotypes.

Boston Life Sciences acquires exclusive license for T-cell switch factor; Potential major benefit in treatment of autoimmune diseases and allergies

Humphreys presented: "Enhanced T Helper Cell Epitope Peptide Vaccines for Melanoma.

Generex Biotechnology Presents Information at the Euroconference Vaccines 3 Meeting of the Pasteur Institute in Paris on the Use of Novel Peptide Vaccine for Melanoma

Cathy Blackwell presented: "Enhanced T Helper Cell Epitope Peptide Vaccines for Melanoma.

Generex Biotechnology Presents Research Abstract on the Use of Novel Peptide Vaccine for Melanoma at the 12th International Congress of Immunology

David Hafler (both Yale University, New Haven and the Broad Institute of the Massachusetts Institute of Technology, MIT, and Harvard University, USA) observed changes in CD4 positive T helper cells (Th) in humans, which were associated with specific dietary habits.