T lymphocyte

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Related to T lymphocyte: B lymphocyte, Cytotoxic T lymphocyte

T lymphocyte

T cell

any of several closely related lymphocytes, developed in the thymus, that circulate in the blood and lymph and regulate the immune system's response to infected or malignant cells. Also called T lymphocyte.

[1965–70; T(hymus-derived)]

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Noun

T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells

T cell

lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection

CD4 cell, CD4 T cell, helper cell, helper T cell - T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus

CD8 cell, CD8 T cell, cytotoxic T cell, killer cell, killer T cell - T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it

References in periodicals archive ?

Abnormalities in CD4+ T lymphocyte subsets in patients with common variable immunodeficiency.

Establishment of T-lymphocyte subset reference intervals in a healthy adult population in Chennai, India

In addition to stimulating B lymphocytes, Th2 cells suppress the cytotoxic T lymphocyte response, decreasing the robustness of cell-mediated immunity.

Emerging infections and pregnancy

Induction of cytotoxic T lymphocyte development from murine thymocytes by IL-1 and IL-6.

Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). II. Effects of DEPs on T-cell-mediated immune responses in rats. (Research)

When a T lymphocyte is activated by a parasite, it commits itself and becomes specific to this parasite, which will thereafter be the only activator of this sensitized lymphocyte.

Thymus: Master Gland of Immunity

Key words: allergy, asthma, dust mites, eosinophil, feed restriction; IgE, immune response, inflammation, lung, T lymphocyte, tumor necrosis factor-[Alpha].

Attenuated Allergic Responses to House Dust Mite Antigen in Feed-Restricted Rats

ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.

Flow cytometry and T-cell response monitoring after smallpox vaccination

The Universite Louis Pasteur researchers tested the response of newborn mice to each type of T lymphocyte and to both together.

New role for immune cells in diabetes

Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization.

Vaccines for mucosal immunity to combat emerging infectious diseases

Washington, January 4 ( ANI ): In a new study, researchers claim to have succeeded for the first time in creating cancer-specific, immune system cells called killer T lymphocytes, from induced pluripotent stem cells (iPS cells).

Cancer-killing technology from induced stem cells created

Also see Evans 2002 (3): "Our findings provide the first evidence that depression may alter the function of killer lymphocytes in HIV-infected women and suggest that depression may decrease natural killer cell activity and lead to an increase in activated CD8 T lymphocytes and viral load" (quote from the abstract).

Chronically depressed women with HIV almost twice as likely as others to die from AIDS-related causes; those with mental-health services had half the death rate of those without

There are, for example, reports demonstrating the feasibility of assessing CD38 expression levels on CD8 + T lymphocytes through quantitative cytometric analyses (3-5).

Quantitating fluorescence intensity from fluorophores: practical use of MESF values

The concentration of CD4 T lymphocytes, the infection-fighting white cells that decline dramatically during the course of AIDS, went from an initial average of 140 cells per cubic millimeter of blood on a slide to a healthier value of 360 cells per cubic millimeter.