T cell

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Related to T lymphocytes: MHC, B lymphocytes, Cytotoxic T lymphocytes

T cell

n.
Any of a class of lymphocytes, including the helper T cells and cytotoxic T lymphocytes, that form in bone marrow and mature in the thymus. T cells are activated when receptors on the cell surface recognize specific antigens. Also called T lymphocyte.

[t(hymus-derived) cell.]

T cell



n.
any of several closely related lymphocytes, developed in the thymus, that circulate in the blood and lymph and regulate the immune system's response to infected or malignant cells. Also called T lymphocyte.
[1965–70; T(hymus-derived)]

T cell

Any of the lymphocytes that act to defend the body against disease by binding foreign antigens to receptors on the surface of their cells. T cells also regulate the function of B cells.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.T cell - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection
CD4 cell, CD4 T cell, helper cell, helper T cell - T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus
CD8 cell, CD8 T cell, cytotoxic T cell, killer cell, killer T cell - T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it
References in periodicals archive ?
Washington, January 4 ( ANI ): In a new study, researchers claim to have succeeded for the first time in creating cancer-specific, immune system cells called killer T lymphocytes, from induced pluripotent stem cells (iPS cells).
The most important effectors of the cell-mediated immune response, cytotoxic T lymphocytes, are the main immune cells that recognize foreign antigens on the surface of infected "self" cells.
Also see Evans 2002 (3): "Our findings provide the first evidence that depression may alter the function of killer lymphocytes in HIV-infected women and suggest that depression may decrease natural killer cell activity and lead to an increase in activated CD8 T lymphocytes and viral load" (quote from the abstract).
At 3 days postinfection, neither DEP exposure nor Listeria infection resulted in significant changes in T lymphocytes when compared with the air-exposed, noninfected control (data not shown).
There are, for example, reports demonstrating the feasibility of assessing CD38 expression levels on CD8 + T lymphocytes through quantitative cytometric analyses (3-5).
It contributes to the development of T lymphocytes, guard cells that participate in immune system reactions.
The concentration of CD4 T lymphocytes, the infection-fighting white cells that decline dramatically during the course of AIDS, went from an initial average of 140 cells per cubic millimeter of blood on a slide to a healthier value of 360 cells per cubic millimeter.
These white cells of the variety known as T lymphocytes, or simply T-cells, were removed earlier and treated so that they contain good copies of the ADA gene for making the crucial enzyme that the girl lacks.
Sustained increases in T lymphocytes as well as in neutrophil and platelet counts were seen, suggesting that Xcellerated T Cells may also have positive effects on elements of the hematological system.
The evaluation of the proportion of polymorphonuclear leukocytes, macrophages, T lymphocytes, and B lymphocytes, as well the relative proportion of neovascularization in skin tissue specimens, was determined by quantitative image analysis (22).
Primary induction of human CD8+ cytotoxic T lymphocytes and interferon-gamma-producing T cells after smallpox vaccination.