T-lymphocyte


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T-lymphocyte

n
(Biochemistry) a type of lymphocyte that matures in the thymus gland and has an important role in the immune response. There are several subclasses: killer T-cells are responsible for killing cells that are infected by a virus; helper T-cells induce other cells (B-lymphocytes) to produce antibodies. Also called: T-cell
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Jurkat E6-1 human T-lymphocyte leukemia cells (purchased from the Type Culture Collection of the Chinese Academy of Sciences, Shanghai, China) were cultured in RPMI-1640 medium containing 10% FBS and 1% antibiotics (penicillin and streptomycin) and incubated at 37[degrees]C in humidified air with 5% CO[sub]2.
Moreover, in terms of the risk factors correlated with postoperative infection in HIV positive patients, Abalo suggested that they were associated with HIV clinical category B, CD4+ T-lymphocyte category of [greater than or equal to] 2, and contaminated wounds.
Ipilimumab is an anticytotoxic T-lymphocyte antigen-4 antibody, while T-VEC is an attenuated herpes simplex 1 virus that expresses the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor.
Fasting blood glucose, fasting insulin, insulin resistance index, and T-lymphocyte messenger RNA levels of glucose transporter 4 (GLUT4, a protein that transports glucose) and glycogen-synthase-kinase-3[beta] (GSK-3P, an enzyme) were determined before and after treatment.
anti-cytotoxic T-lymphocyte associated protein 4 (CTLA-4) and anti-programmed cell death protein 1 cancer immunotherapy (PD-1)] (2, 3).
Differential cells profiles analysis (flowcytometry technique) of lymphocytes, neutrophils, B-Cells, as well as, CD4 and CD8 T-lymphocyte showed that treatment with the extraction has maintained the populations of these cells significantly, treated group showed increment in the cell percentages of CD4 (24%), lymphocytes (23%), neutrophils (19.
Global Markets Direct's, 'Cytotoxic T-Lymphocyte Protein 4 (CTLA-4 or CD152) - Pipeline Review, H1 2016', provides in depth analysis on Cytotoxic T-Lymphocyte Protein 4 (CTLA-4 or CD152) targeted pipeline therapeutics.
According to the company, AGEN1884 is an immune checkpoint modulator (CPM) antibody that binds to cytotoxic T-lymphocyte antigen-4 (CTLA-4).
EVs released from regulatory T cells are able to inhibit DC-induced cytotoxic T-lymphocyte (CTL) responses [21].
Table 9: Distribution of the HIV seropositive cases with respect to CD8 +T-lymphocyte cell count Sex CD8+ T-lymphocyte cell count Male (%) Female (%) Total (%) Below 200 4(4) 3(3) 7(7) 200-400 16(15) 2(2) 18(17) 400-600 15(14) 7(6) 22(20) 600-800 16(15) 5(5) 21(20) 800-1000 5(5) 4(4) 9(9) 1000-1200 6(6) 6(6) 12(12) 1200-1400 4(4) 2(2) 6(6) 1400-1600 4(4) 1(1) 5(5) 1600 and above 2(2) 2(2) 4(4) Total 72(69) 32(31) 104(100).
The neoplastic cells exhibited only CD3 reactivity, indicating a T-lymphocyte origin (Fig 1), while CK-positive cells were organized as normal thymic epithelial networks (Fig 2).