T-lymphocyte

(redirected from T-lymphocytes)
Also found in: Thesaurus, Medical, Encyclopedia.
Related to T-lymphocytes: thymus gland, B-lymphocytes

T-lymphocyte

n
(Biochemistry) a type of lymphocyte that matures in the thymus gland and has an important role in the immune response. There are several subclasses: killer T-cells are responsible for killing cells that are infected by a virus; helper T-cells induce other cells (B-lymphocytes) to produce antibodies. Also called: T-cell
References in periodicals archive ?
17] Therefore, in the present study, we investigated the role of MFN2 in mediating the immune function of T-lymphocytes in vitro and determined whether MFN2-mediated regulation of T cells was associated with the Ca 2+-calcineurin-NFAT pathway.
IMT-002 occupies the peptide binding groove of DQ8 present on the surface of antigen presenting cells where diabetogenic peptides such as insulin are presented to CD4 T-lymphocytes to initiate the autoimmune cascade.
The CKIs that target T-lymphocytes have revolutionized oncologic practice, with several products in this class leading to sustained tumour reductions.
Infected with the harmless designer virus, it enabled the immune system to recognize these cancer proteins as dangerous, allowing the body to create a "powerful army of cytotoxic T-lymphocytes, also known as killer cells, which identified the cancer cells through their protein and successfully destroyed them.
It is able to block the interaction between PD-1 and its ligands, PD-L1 and PD-L2, to activate T-lymphocytes which may affect both tumour cells and healthy cells.
T-lymphocytes were isolated from whole blood at four points (before anesthesia, before CPB, at 2 and 4 h after beginning CPB) for intracellular microRNA-125a expression by quantitative real-time reverse transcription polymerase chain reaction in 14 patients.
They play a major role in maintaining the patient nutritional status by regulating normal body weight, leads to infiltration of T-lymphocytes and modulate the immune system, Triggers the immune function and leukocytes anti-oxidant defense capacity in malignancy and strengthen the adaptation towards systemic inflammation, enhance the Wound healing by increasing the formation of Collagen, checked by Hydroxyphiline production, an index of collagen formation.
They capture invading pathogens and present the antigenic components to T-lymphocytes, activating the acquired immune pathway.
In a recent article published in Scientific Reports magazine, genetic scientists wrote that CRISPR/Cas9 technology is able to remove HIV virogenes from infected T-lymphocytes which the virus usually attacks.
Keytruda blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2, thereby activating T-lymphocytes, which may affect both tumor cells and healthy cells.
This method was used to isolate at least 95% of T-lymphocytes according to the data from Patel et al.
The CDC-XM method is based on incubation of donor isolated B- and T-lymphocytes with recipient serum.