TNF

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TNF

abbr.
tumor necrosis factor
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.TNF - a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
References in periodicals archive ?
To address this, we have now measured the concentrations of proinflammatory cytokines TNF-a, IL-1[sz], IL-6, and IL-17 and 11 CXC and CC chemokines in bronchial alveolar lavage fluid from a large cohort of 100 subjects (asthmatics = 70, including 37 mild and 33 moderate/severe asthmatics, and controls = 30).
So the expression level of TNF-a is not only dependent on time and dose of the stimulants but different organs also.
In patients with CHD, leptin, ghrelin and tumour TNF-a serum levels appear to regulate nutrient intake, growth, weight and energy intake and output.
TNF-a receptor fusion protein prevents experimental auto-immune encephalomyelitis and demyelination in Lewis rats: an overview.
The researchers observed increased levels of inflammatory molecules, including TNF-a during fracture healing.
We found a significantly higher amount of TNF-a in all saliva samples obtained from patients with periodontitis in comparison with the healthy controls.
One-way analysis of variance revealed no statistically significant differences for TNF-a and TNF-R p75 levels between groups (with or without PTSD).
The study showed that after receiving treatment for the gum disease, improvement in rheumatoid arthritis symptoms was seen in patients who did and did not receive the anti-TNF-a medications which block the production of TNF-a that aggravate or can cause inflammation.
The cytotoxic effects of TNF-a are suggested to be partly mediated by reactive oxygen species (ROS)- and mitochondria-dependent apoptosis.