Taurocholic

Related to Taurocholic: Sodium taurocholate

Tau`ro`chol´ic


a.1.(Physiol. Chem.) Pertaining to, or designating, a conjugate acid (called taurocholic acid) composed of taurine and cholic acid, present abundantly in human bile and in that of carnivora. It is exceedingly deliquescent, and hence appears generally as a thick, gummy mass, easily soluble in water and alcohol. It has a bitter taste.
Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
References in periodicals archive ?
"Intestinal taurine and the enterohepatic circulation of taurocholic acid in the cat." Advances in Experimental Medicine and Biology 1992; 315:45-54.
For calibration of the mass spectrometer, caffeine, N-butylamine, buspirone hydrochloride, sodium dodecyl sulfate and taurocholic acid (Sigma-Aldrich, St Louis, Missouri, USA) besides Ultramark 1621 (Alfa Aesar, Heysam, UK), were used as standards.
made a combination of nanoparticles, Emodin-Loaded PLGA-TPGS and Heparin Sodium-Loaded PLGA-TPGS ones for chemotherapeutic purposes [56]; colon cancer (oral absorption mechanism and antiangiogenesis effect of taurocholic acid linked heparin docetaxel conjugates) [57]; lung, melanoma, and ovarian cancers [58-61]; melanoma [62]; and heart, spleen, lung, and kidney [63-65].
emphasized that conjugated bile acid taurocholic acid-(TCA-) mediated S1PR2 signaling could promote neuroinflammation during hepatic encephalopathy [29].
(28) demonstrated the effects of tocilizumab on experimental severe AP and associated acute lung injury in taurocholic acid model.
Reaction volume of 200 [micro]L, containing different concentrations of bark extracts (assay concentrations: 100, 50, 25, 12.5, 6.25, and 3.125 [micro]g/mL), was preincubated with 50 [micro]L of 24 mM taurocholic acid, 5 [micro]L of 8 mM p-NPB in acetonitrile in 0.1 M sodium phosphate buffer, 0.1 M NaCl, pH 7.0 at 25[degrees] C for 10 min.
According to the composition of human bile acids, the following mixture (36 mmol/L) was prepared in phosphate buffer (0.1 M): taurodeoxycholic acid, glycocholic acid, glycodeoxycholic acid, glycochenocholic acid, and taurocholic acid.
Determination of bile salts deconjugation (taurocholic acid and glychocolic acid)
These new solution certified reference materials (CRMs) consist of lithocholic acid, taurocholic acid and native and deuterium-labeled analogs of cholic acid, chenodeoxycholic acid, deoxycholic acid and ursodeoxycholic acid.
External bile acid standards, including cholic acid (CA), lithocholic acid (LCA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), ursodeoxycholic acid (UDCA), [alpha]-muricholic acid ([alpha]MCA), [beta]-muricholic acid ([beta]MCA), [omega]-muricholic acid ([omega]MCA), glycocholic acid (GCA), glycochenodeoxycholic acid (GCDCA), taurocholic acid (TCA), taurodeoxycholic acid (TDCA), tauro chenodeoxycholic acid (TCDCA), taurolithocholic acid (TLCA), tauro-[alpha]-muricholic acid (T[alpha]MCA), and tauro-[beta]-muricholic acid (T[beta]MCA), were purchased from Sigma-Aldrich.
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/-mice.
Musch et al., "Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 -/- mice," Nature, vol.