tazobactam

(redirected from Tazobactam sodium)
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ta·zo·bac·tam

 (tā′zō-băk′tăm)
n.
A compound, C10H12N4O5S, that inhibits action of the enzyme beta-lactamase, thus counteracting bacterial resistance to beta-lactam antibiotics. It is used in its sodium form in combination with piperacillin to treat infections caused by antibiotic-resistant bacteria.

[Probably t(ri)- + azo- + -bactam, suffix for inhibitors of beta-lactamase, bacterial enzyme conferring resistance to certain antibiotics (b(eta)- + lactamase).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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References in periodicals archive ?
ZERBAXA is an antibacterial combination product for intravenous infusion consisting of the cephalosporin antibacterial drug ceftolozane sulfate and the beta-lactamase inhibitor tazobactam sodium.
According to the company, ZERBAXA is an antibacterial combination product for intravenous infusion consisting of the cephalosporin antibacterial drug ceftolozane sulfate and the beta-lactamase inhibitor tazobactam sodium.
Tazobactam sodium, a derivative of the penicillin nucleus, is a penicillanic acid sulfone and is an irreversible inhibitor of many [beta]-lactamases (ie, it binds to [beta]-lactamases more readily than piperacillin).