Tazobactam sodium - definition of Tazobactam sodium by The Free Dictionary
tazobactam (redirected from Tazobactam sodium)
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A compound, C10H12N4O5S, that inhibits action of the enzyme beta-lactamase, thus counteracting bacterial resistance to beta-lactam antibiotics. It is used in its sodium form in combination with piperacillin to treat infections caused by antibiotic-resistant bacteria.
, suffix for inhibitors of beta-lactamase, bacterial enzyme conferring resistance to certain antibiotics
(b(eta)- + lactamase).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive
ZERBAXA is an antibacterial combination product for intravenous infusion consisting of the cephalosporin antibacterial drug ceftolozane sulfate and the beta-lactamase inhibitor tazobactam sodium
According to the company, ZERBAXA is an antibacterial combination product for intravenous infusion consisting of the cephalosporin antibacterial drug ceftolozane sulfate and the beta-lactamase inhibitor tazobactam sodium
, a derivative of the penicillin nucleus, is a penicillanic acid sulfone and is an irreversible inhibitor of many [beta]-lactamases (ie, it binds to [beta]-lactamases more readily than piperacillin).