Most of the multidrug resistant isolates were sensitive to Polymyxins B, Tazocin
and Fusidic acid (Fig.
Keyword: ESBL, UTI, Piperacillin Tazocin
The ecology of antibiotic use in the ICU: homogeneous prescribing of cefepime but not tazocin
selects for antibiotic resistant infection.
Eighteen (72%) patients were treated with ciprofloxacin (Cipro 400 mg flakon, Biopharma, Istanbul, Turkey), two (8%) patients with ciprofloxacin (Cipro 400 mg flakon, Biopharma, Istanbul, Turkey) and piperacillin tazobactam (Tazocin
4.5 g flakon, Pfizer, New York, USA), two (8%) patients with meropenem (Meronem 1 g flakon, Astra Zeneca, Cambridge, England), two (8%) patients with ciprofloxacin (Cipro 400 mg flakon, Biopharma, Istanbul, Turkey) and daptomycin (Cubicin 500 mg flakon, Novartis, Basel, Switzerland), and one (4%) patient with meropenem (Meronem 1 g flakon, Astra Zeneca, Cambridge, England) and linezolid (Zyvoxid 600 mg flakon, Pfizer, New York, USA).
Multi drug resistance pattern of Klebsiella pneumoniae (n=9) showed 9 (100%) resistance to Ampicillin, 7 (77.8%) to Ciprofloxacin, 6 (66.7%) to Cotrimoxazole, Clavulanic acid-Amoxicillin, Gentamycin and Tigecycline, 5 (55.6%) to Ceftriaxone and Sulbactam-piperacillin (Combicin), 4 (44.4%) to Tazobactum-piperacillin (Tazocin
), 3 (33.3%) Amikacin, Imepenim and Doxycycline.
The cause of her symptoms was not identified and the patient was treated prophylactically for Sepsis of Unknown Origin (SUO) with IV tazocin
for five days.
Afterwards, patient clinically improved and was resumed on intravenous vancomycin and Tazocin
. Ten days later, patient was discharged home on Rifampicin and Ciprofloxacin for a total of 12-week course.
Tazobactam with piperacillin (Tazocin
) was administered as per local guidelines.
The patient received piperacillin-tazobactam (Tazocin
) along with total parenteral nutrition.
67y old 14 days Pneumonia, then Ribs 7,8,9 male ventilator dependence left (fully treated with Tazocin
The ciprofloxacine treatment was changed after 16 days to intravenous vancomycin 2x1 g (Edicin, Lek farmacevtska druzba d.d.; Ljubljana, Slovenia) and piperacillin/tazobactam 3x4.5 g (Tazocin
, Wyeth Lederle S.p.A.; Catania, Italy) daily, according to the recommendation of the clinical pharmacologist.
The lowest rates of resistance were detected for: tazocin
(6.25%), amikacin (12.5%) and gentamicin (14.84%).