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An injectable drug containing an isotope of the radioactive element technetium, used in nuclear medicine imaging primarily to visualize the heart muscle, parathyroid glands, and breast tissue.

[sesta-, perhaps alteration (influenced by Latin sex, six) of hexakis-, prefix indicating six in chemical names (from the six ligands bound to its central technetium ion ) + m(ethoxy)i(so)b(utyl)i(sonitrile).]
References in periodicals archive ?
The two most commonly used localization modalities include ultrasonography and technetium Tc 99m sestamibi scan.
Localization of parathyroid adenomas by sonography and technetium tc 99m sestamibi single-photon emission computed tomography before minimally invasive parathyroidectomy: Are both studies really needed?
Nuclear medicine scans using technetium Tc 99m sestamibi can help physicians determine which breast cancer patients will respond to chemotherapy and which patients won't, according to results of a phase II clinical trial published in the June issue of the Journal of Nuclear Medicine.
Tc-99m is also used with Cardiolite([R]) (Kit for the Preparation of Technetium Tc 99m Sestamibi for Injection), the most successful radiopharmaceutical agent, which has been used to image more than 40 million patients.
The most common of these are perfusion thallium Tl 201, technetium Tc 99m sestamibi, technetium Tc 99m tetrofosmin and the bone-imaging agent technetium Tc 99m methylene diphosphonate.