tenofovir


Also found in: Medical, Wikipedia.

te·nof·o·vir

 (tə-nŏf′ə-vîr)
n.
An antiviral drug, C9H14N5O4P, used in the form of a prodrug (tenofovir disoproxil fumarate) to treat chronic hepatitis B and, in combination with other drugs, to treat HIV infection or to reduce the risk of HIV infection.

[teno-, of unknown origin + fo- (alteration of pho(spho)-) + (anti)vir(al).]
Translations

tenofovir

n tenofovir m
Mentioned in ?
References in periodicals archive ?
Symfi Lo (efavirenz, lamivudine and tenofovir disoproxil fumarate) 400 mg/300 mg/300 mg tablets is a once-daily, single-tablet regimen (STR) and is indicated as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adult and pediatric patients weighing at least 35 kg.
Cimduo (lamivudine and tenofovir disoproxil fumarate) 300 mg/300 mg tablets is a once-daily combination of two nucleo(t)side reverse transcriptase inhibitors and is indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and pediatric patients weighing at least 35 kg, added the company.
Here, we report a case of a patient who developed LCV almost one month after the use of tenofovir.
Background: Tenofovir disoproxil (TDF) is a promising salvage therapy for patients with chronic hepatitis B (CHB) who failed regimens of other nucleoside analogues (NAs).
Dolutegravir plus tenofovir disoproxil fumarate/emtricitabine (Tivicay plus Truvada).
One of the most commonly used drug among them for the first line therapy is Tenofovir Disoproxil Fumarate (TDF).
Tenofovir is associated with kidney toxicity, [1] and estimated probabilities of tenofovir discontinuation as a result of kidney toxicity in cohort studies (with durations of follow-up longer than a year) range from 2.
Emtricitabine and tenofovir alafenamide are from Gilead and rilpivirine is from Janssen Sciences Ireland UC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson.
Food and Drug Administration announced today its approval of a new all-in-one pill to treat HIV patients that includes a new version of the drug tenofovir, which researchers think will help reduce side effects from the multi-drug regimens used for HIV, UPI reported.
1) Failure to follow the treatment protocol may have contributed to the lack of efficacy: Although the mean rate of adherence was 86-90% (depending on the method of assessment), tenofovir was detected in only 25-30% of plasma samples from a random sample of participants assigned to one of the intervention regimens.
Wyatt: So far the data have not suggested that a patient with established chronic kidney disease--say someone with diabetic nephropathy--is necessarily at higher risk of tenofovir toxicity than someone who has normal kidney function, as long as the drug is dosed appropriately.
13 ( ANI ): Researchers have developed a new intravaginal ring (IVR) developed for the sustained 90-day co-delivery of tenofovir and levonorgestrel, an anti-human immunodeficiency virus (HIV) drug and a contraceptive.