The drug combinations most associated with depression included the beta-blockers metoprolol (Lopressor, Toprol) and atenolol (Tenormin
), which are used to treat high blood pressure and other cardiovascular issues; the proton pump inhibitor omeprazole (Prilosec), used to treat gastroesophageal disease; the painkiller hydrocodone (Vicodin); and the anticonvulsant drug gabapentin (Neurontin), which is used to treat epilepsy and nerve pain.
> Beta blockers, including atenolol (Tenormin
), Carvedilol (Coreg), and metoprolol (Toprol XL, Lopressor)
Relatively low risk: Parkinson's disease medications such as levodopa/carbidopa (Parcopa, Sinemet) and amantadine; antihypertensive drugs such as Clonidine hydrochloride (Catapres); calcium channel blockers, such as diltiazem (including Cardizem and Dilacor), and verapamil (Calan); beta-blockers, such as atenolol (Tenormin
), propanolol (Inderal) and timolol (Timoptic); the Alzheimer's disease drug donepezil (Aricept); hormone replacement drugs, such as estrogen (Enjuvia, Cenextin, etc.), medroxyprogesterone (Provera) and conjugated estrogens/medroxyprogesterone (Prempro); and benzodiazepines, such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan) and estazolam (ProSom).
The other prescription drugs at the onset of treatment are beta blockers, whether propranolol (Inderal), atenolol (Tenormin
), nadolol (Corgard), or metoprolol (Lopressor, Toprol XL).
BETA BLOCKERS: These Nausea, stomach Lopressor and Toprol drugs interrupt, or cramps, depression, XL (metoprolol); block, specific sleep disturbance, Corgard (nadolol); command signals to sexual dysfunction, Tenormin
(atenolol); cells in the walls dizziness and Sectral of blood vessels and blurred vision.
The researchers also found that taking oral beta blockers such as Tenormin
and Lopressor was associated with a 71 percent increase in the risk of neovascular AMD, a more advanced and vision-threatening form of the disease.
* Beta-blockers, including propranolol (Inderal) and atenolol (Tenormin
), reduce the effects of adrenaline by blocking cellular receptors for adrenaline.
Common beta-blockers include metroprolol ( Lopressor, Toprol XL), atenolol (Tenormin
), carvedilol (Coreg), nadolol (Corgard) and propranolol (Inderal).
They include drugs for high blood pressure (e.g., Minipress, Cardura, Hytrin), diabetes (e.g., Avandia, Diabinese, Orinase) and heart conditions (e.g., Inderal, Lopressor, Toprol, Tenormin
In particular, Zeneca has been very actively promoting its plain betablocker Tenormin
as a competitive alternative to Astra's largest selling betablocker in those countries.