therapeutic index

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Related to Therapeutic dose: Toxic Dose

therapeutic index

n.
The ratio between the toxic dose and the therapeutic dose of a drug, used as a measure of the relative safety of the drug for a particular treatment.

ther′apeu′tic in′dex



n.
the ratio between the dosage of a drug that causes a lethal effect and the dosage that causes a therapeutic effect.
[1925–30]
References in periodicals archive ?
Electronic auction: supply of the consumable material for work on the automatic blood separator "macopresssmart", which allows to obtain not less than one dose of red blood cells in the additional solution, at least one dose of fresh frozen plasma, at least one dose of platelets from the blood dose, followed by bulleting into the therapeutic dose according to the application of the bryansk regional blood transfusion station "
The NKTR-181 HAP study was designed to confirm and assess the relative oral abuse potential of NKTR-181 at its maximum analgesic or therapeutic dose (400 mg) and at a supratherapeutic dose (3 times to 12 times greater than its analgesic dose range of 100 mg to 400 mg) compared to common therapeutic doses of a Schedule II opioid, oxycodone.
Initial results from the firm's completed single ascending dose study indicated a potentially therapeutic dose range for d-Methadone without the side effects typically observed with racemic methadone in opioid naive subjects or with other NMDA inhibitors, such as ketamine.
However Mrs Bolton told the jury and assistant coroner Malcolm Donnelly that the level of the drug found could be within the range of therapeutic dose.
6 mg BID, a therapeutic dose of cyclosporine, flurazepam, gabapentin, levothyroxine, mirtazapine, oxycodone, prednisone, and premarin.
Amorcyte demonstrated in its Phase 1 trial that AMR-001 preserved heart muscle function when a therapeutic dose of cells was administered.
We have designed original software named PharmCalculation, which counts cost of monotherapy within one month for various antihypertensive generics, using the median therapeutic dose as a starting point for each drug and mean price on the pharmaceutical market.
In line with these findings, a thorough ECG study demonstrated that Defibrotide did not prolong QT/QTc interval in healthy human volunteers at either the therapeutic dose (6.
The result is a clinical therapeutic dose equivalent to apheresis platelets but typically at a lower cost to produce.
1) Improving patients' well-being rather than arriving at a predetermined therapeutic dose should guide treatment.
Desvenlafaxine is unique because the starting dose is the recommended therapeutic dose (50 mg once daily).
Further forensic analysis revealed Mrs Wright had taken a prescribed drug but only in a therapeutic dose.
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