To run mad

To become wild with excitement
To run wildly about under the influence of hydrophobia; to become affected with hydrophobia.
See under Mad.

See also: Mad, Mad, Run

Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
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On his coming out, the concourse made at him anew, weeping, embracing, and shouting, all by turns and all together, until the very tide of the river on the bank of which the mad scene was acted, seemed to run mad, like the people on the shore.
'Time was, now, I remember, when I was like to run mad with the desire to wear a coat of that colour.
Also wives of two governors should pray very well not to run mad.
WILLIE MULLINS is hoping ground conditions will improve sufficiently for him to run Mad Fish, his highly regarded bumper horse, before the Weatherbys Champion Bumper next month.
A very suitable place, to my mind, for a girl to run mad and die of a heart attack.