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Related to Toprol-XL: metoprolol, Metoprolol succinate


 (tŏp′rôl′, -rŏl′)
A trademark for an extended-release formulation of the succinate salt of metoprolol.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
M2 PHARMA-November 30, 2017-Lannett grants the distribution rights for authorized generic version of Toprol-XL to Aralez Pharmaceuticals
M2 EQUITYBITES-November 30, 2017-Lannett grants the distribution rights for authorized generic version of Toprol-XL to Aralez Pharmaceuticals
The ARCA amended SPA submission details a single adequate and well-controlled Phase 3 clinical trial designed as a double-blind, active-controlled, multicenter, international, study comparing Gencaro with Toprol-XL for the prevention of recurrent AF or all-cause mortality, or ACM, in HF patients with mid-range ejection fraction, or HFmrEF, which is defined as HF with a left ventricular ejection fraction.
Potential new medicines for congestive heart failure include Atacand, Avapro, Dilatrend, Diovan, Enbrel, eplerenone, Natrecor, Remicade, Toprol-XL and Vanlev.
In 2003, TOPROL-XL had United States sales of $909m.
* Atenolol (Tenormin), metoprolol (Lopressor, Toprol-XL), diltiazem, and verapamil are optimal choices for rate control during exercise and at rest.
Drug specialist Astra Zeneca was the heaviest faller, off 4.3 per cent, after a US judge ruled that rivals could launch copies of its heart drug Toprol-XL. Ryanair dropped 1.3 per cent amid a fierce row with a trader who said the airline was cancelling dozens of flights out of Luton and Stansted.
Metoprolol succinate extended-release tablets (Toprol-XL, AstraZeneca) are indicated for treatment of New York Heart Association class II and III patients with heart failure of ischemic, hypertensive, or cardiomyopathic origin.
The study was sponsored by AstraZeneca Pharmaceuticals LP, which markets long-acting metoprolol (Toprol-XL).
Despite several attempts of cardioversion and two ablations, my heart went from alternating between normal rhythm and A-fib to constant A-fib despite massive dosages of Toprol-XL and amiodarone.
To conserve available drug for those with the greatest need, the company asked that new patients with mild or moderate heart failure or essential hypertension not be started on Coreg and that a switch to Toprol-XL (metoprolol) be considered for those with mild to moderate heart failure who are already being treated with carvedilol; metoprolol is the only other [beta]-blocker approved for use in this population.