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Related to Totipotent stem cells: Pluripotent stem cells


 (tō-tĭp′ə-tənt, tō′tĭ-pōt′nt)
Relating to a cell, especially a fertilized egg, that is capable of differentiating into an unlimited number of specialized cell types.

to·tip′o·ten·cy n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.totipotency - the ability of a cell to give rise to unlike cells and so to develop a new organism or part; "animal cells lose their totipotency at an early stage in embryonic development"
ability - the quality of being able to perform; a quality that permits or facilitates achievement or accomplishment
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


, totipotence
n. totipotencia, habilidad de una célula de regenerarse o desarrollarse en otro tipo de célula.
English-Spanish Medical Dictionary © Farlex 2012
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References in periodicals archive ?
ESCs are totipotent stem cells that had a capability to proliferate and differentiate into appropriate lineages to form specialized cells and organs and play a central role in the developmental process [7].
What totipotent stem cells can do that pluripotent ones can't do, however, is develop into tissues that support the embryo, like the placenta.
Stem cells can be categorised in different ways based on potency - unipotent stem cells can form only one type of cell, multipotent stem cells can form multiple cell types, pluripotent stem cells can form most types of cells and totipotent stem cells can form all types of cells and specialised tissues that support development of the embryo.
(5,6) The stem cells are also divided into totipotent stem cells (e.g., fertilized egg cell or zygote), that can generate all cell and tissue types present in an organism; Pluripotent stem cells (like embryonic stem cells) can generate the majority of cell and tissue types present in an organism; multipotent stem cells (like mesenchymal stem cells [MSC]) can generate a limited number of cell and tissue types, usually dependent on their germ layer of origin.
Embryonic stem cells, including totipotent stem cells (produced from fusion of egg and sperm), and pluripotent stem cells (5-14 day old blastocytes) have a strong potency of cell reproducing and potentially highly teratogenic.
But the problem is there are very few totipotent stem cells in adults while harvesting them from embryos is very controversial.
Because this "potential space" contains residual totipotent stem cells, a wide variety of neoplasia can develop here and it can present throughout life.