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Related to Tricyclics: Heterocyclics, MAOIs


 (trī-sĭk′lĭk, -sī′klĭk)
Having or being a molecular structure that contains three closed rings: a tricyclic molecule.
A tricyclic antidepressant drug.


(Chemistry) (of a chemical compound) containing three rings in the molecular structure
(Pharmacology) an antidepressant drug having a tricyclic molecular structure


(traɪˈsaɪ klɪk, -ˈsɪk lɪk)

1. pertaining to or embodying three cycles.
2. having a three-ring chemical structure.
3. Also called tricy′clic antidepres′sant. any of a group of pharmacologically active substances that share a common three-ring structure, used to treat depression and cocaine abuse.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tricyclic - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
amitriptyline, amitriptyline hydrochloride, Elavil - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications
antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects
clomipramine - a tricyclic antidepressant drug
desipramine - a tricyclic antidepressant drug that activates the psychomotor system
Adapin, doxepin, doxepin hydrochloride, Sinequan - a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)
Imavate, imipramine, impramine hydrochloride, Tofranil - a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression
nortriptyline, Pamelor - a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs
protriptyline - tricyclic antidepressant used to treat clinical depression
Surmontil, trimipramine - tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia
References in periodicals archive ?
In the case of antidepressants, tricyclics might increase the risk of falls and fractures by blocking alpha-adrenergic, [H.
Apparently depression ran in this man's family, and when he took an overdose of his tricyclic antidepressant, he also took the tricyclics of his mother and his sister.
Antispasmodics and tricyclics alleviate abdominal pain
cohort study has shown that tricyclics may be safer for ^treating depression in people older than 65 years than are the more commonly prescribed selective serotonin reuptake inhibitors.
cohort study has shown that tricyclics may be safer for treating depression in people older than 65 years than are the more commonly prescribed selective serotonin reuptake inhibitors.
She goes on to say that tricyclics can cause potentially unpleasant or dangerous side-effects like confusion, dry mouth, worsening of glaucoma, constipation, and urinary retention.
This suggests that there may be some characteristic of tricyclics that is raising the risk.
Tricyclics affect both norepinephrine and serotonin.
The toxic effects of tricyclics are caused by four main pharmacological properties: inhibition of norepinephrine reuptake at nerve terminals, direct alfa- adrenergic block, a membrane stabilizing or quinidine-like effect on the myocardium and anticholinergic action.
Children treated with tricyclics also were more likely to still need gastrointestinal medication at follow-up.
Effexor, Cymbalta, and Remeron, a newer group of antidepressants, boost brain levels of serotonin and norepinephrine, like the tricyclics.
SSRIs and tricyclics have fewer side effects than MAOIs, but tricyclics are used to treat depression for longer periods.