co-trimoxazole

(redirected from Trimethoprim-sulfamethoxazole)
Also found in: Medical, Acronyms.
Related to Trimethoprim-sulfamethoxazole: nitrofurantoin, ciprofloxacin, Bactrim

co-trimoxazole

(ˌkəʊtrɪˈmɒksəzəʊl)
n
(Pharmacology) an antibiotic consisting of a mixture of trimethoprim and sulfamethoxazole (a sulfa drug): used esp to treat infections of the urinary tract and lungs (as in AIDS)
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Patients taking ciprofloxacin experienced fewer side effects, and the drug was found to be at least as effective as the longer regimen of trimethoprim-sulfamethoxazole (JAMA 283:1583-1590,2000).
Overall, 28 isolates (90%) were resistant to ampicillin and trimethoprim-sulfamethoxazole.
coli isolates was significantly associated with nonsusceptibity to gentamicin, tobramycin, ciprofloxacin, chloramphenicol, and trimethoprim-sulfamethoxazole (Table 1).
A combination of atovaquone-azithromycin (AT-AZ) is as effective as trimethoprim-sulfamethoxazole (TMP-SMZ) for the prevention of serious bacterial infections in children with HIV aged 3 months to 19 years, said Walter T.
DENVER--Acute sinusitis symptoms and quality of life improved equally well in 11 patients treated with the third-generation cephalosporin ceftibuten and in 20 patients given the less expensive antibiotics amoxicillin or trimethoprim-sulfamethoxazole, Dr.
Moreover, virtually all community-acquired MRSA associated with skin and soft tissue infection is susceptible to trimethoprim-sulfamethoxazole.
The isolates were found mostly in wounds but were also detected in blood, ear, respiratory, and other specimens; all were susceptible to ciprofloxacin, gentamicin, and trimethoprim-sulfamethoxazole.
In a study of 105 diabetic women with asymptomatic bacteriuria, 43 of the 55 who were randomized to receive trimethoprim-sulfamethoxazole developed symptomatic bacteriuria in up to 3 years of follow-up, compared with 44 of the 50 who received placebo--a nonsignificant difference, reported Dr.
Special cultures for mycobacteria permitted the growth of Mycobacterium chelonae, which was sensitive to amikacin and clarithromycin and resistant to imipenem-cilastatin, fluoroquinolones, and trimethoprim-sulfamethoxazole.
Hobson-Webb presented a case study of a 15-year-old black girl who had taken a 3-day course of metronidazole for bacterial vaginitis; she had been unresponsive to a prior course of trimethoprim-sulfamethoxazole.
The isolate was resistant to cephalothin, ceftazidime, cefoxitin, and ceftriaxone and was sensitive to trimethoprim-sulfamethoxazole, amikacin, gentamicin, chloramphenicol, ciprofloxacin, and meropenem.
Of the 46 MRSA isolates identified in 2004, 45 were susceptible to gentamicin, rifampin, and trimethoprim-sulfamethoxazole.