co-trimoxazole

(redirected from Trimethoprim-sulfamethoxazole)
Also found in: Medical, Acronyms.
Related to Trimethoprim-sulfamethoxazole: nitrofurantoin, ciprofloxacin, Bactrim

co-trimoxazole

(ˌkəʊtrɪˈmɒksəzəʊl)
n
(Pharmacology) an antibiotic consisting of a mixture of trimethoprim and sulfamethoxazole (a sulfa drug): used esp to treat infections of the urinary tract and lungs (as in AIDS)
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Ninety percent of the 252 isolates with resistance information had predicted resistance to trimethoprim-sulfamethoxazole, tetracycline, and chloramphenicol and decreased susceptibility to azithromycin.
TRIMETHOPRIM-SULFAMETHOXAZOLE (TMP-SMX) was linked to severe acute respiratory distress syndrome (ARDS) in five previously healthy teens aged 13-18 years.
The animal recovered successfully after treatment with metronidazole and trimethoprim-sulfamethoxazole and was later released in a suitable habitat.
The study developed statistical methods to predict phenotypic resistance from resistance genes for various combinations of the four bacterial species and the antibiotics gentamicin, tobramycin, ciprofloxacin, levofloxacin, trimethoprim-sulfamethoxazole, ertapenem, imipenem, cefazolin, cefepime, cefotaxime, ceftazidime, ceftriaxone, ampicillin, piperacillin and aztreonam.
[5] Patients with PJP require high doses of trimethoprim-sulfamethoxazole, which may cause life-threatening complications in the context of kidney disease.
The antibacterial agents tested for sensitivity were (Penicillin 1U), Ceftriaxone (30ug), Ceftazidime (30ug), Cefotaxime (30ug), Amoxycillin - Clavulanic Acid (20/10ug), Amikacin (30ug), Piperacillin - Tazobac tam (100/10ug), Trimethoprim-Sulfamethoxazole (1.25/23.75ug), Imipenem (10ug), Ciprofloxacin (5ug), Norfloxacin (10ug), Ofloxacin (5ug).
After their abscess was drained, patients were randomly assigned to receive either clindamycin (300 mg 3 times daily) or trimethoprim-sulfamethoxazole (80 mg/ 400 mg twice daily) or placebo for 10 days.
Among pregnant women with UTIs, the most frequently prescribed antibiotics during the first trimester were nitrofurantoin, ciprofloxacin, cephalexin, and trimethoprim-sulfamethoxazole. Given the potential risks associated with use of some of these antibiotics in early pregnancy and the potential for unrecognized pregnancy, women's health care providers should be familiar with the ACOG recommendations and consider the possibility of early pregnancy when treating women of reproductive age.
Extremely high incidence of macrolide and trimethoprim-sulfamethoxazole resistance among clinical isolates of Streptococcus pneumoniae in Taiwan.J ClinMicrobiol 1999;37:897-901.
Several drugs have been proposed for treatment, including pyrimethamine, sulfadiazine, spiramycin, clindamycin, and trimethoprim-sulfamethoxazole [8].
amoxicillin-clavulanate, trimethoprim-sulfamethoxazole, cefazolin, cefuroxime, ceftriaxone, cefixime (first, second and third generation cephalosporins), amikacin (an aminoglycoside) and ciprofloxacin (a fluoroquinoline) was identified.
These isolates were also subjected to susceptibility testing and polymerase chain reaction for four groups of genes including int encoding integron elements, sull and sulll encoding trimethoprim-sulfamethoxazole resistance and smqnr encoding quinolone resistance.