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Any of a class of drugs that act as agonists of serotonin, result in cranial vasoconstriction, and are used for the prophylaxis and treatment of migraine headaches.

[From -triptan, triptan suffix, shortening and alteration of tryptamine.]


(Pharmacology) any of various drugs used to treat migraine headaches
References in periodicals archive ?
Zosano Pharma announced that the previously announced Notice of Allowance of our patent application titled "Method of Rapidly Achieving Therapeutic Concentrations of Triptans for Treatment of Migraines" has resulted in the issuance of a U.
The last occurred 30 years ago with the development of triptans.
7) The evidence that triptans and serotonin receptor agonists are effective in the treatment of migraine also supports the theory that serotonin neurohormonal signaling pathways play a critical role in the pathogenesis of migraines.
In 2006, the Food and Drug Administration released an alert on serotonin syndrome occurring with combined use of selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) with triptans.
Triptans are most commonly administered orally, usually as a pill.
Most of the triptans are categorized as substrates of these enzymes, with the exception of eletriptan, which is categorized as both a substrate and an inducer.
Acute migraine treatment market is dominant by Triptans and most of them are available as pills.
Seven triptans are available, including two that are approved for use in children; rizitriptan (Maxalt) is approved for children older than age 6 years, and almitriptan (Axert) is approved for those aged 12-17 years.
UKPRwire, Thu Aug 15 2013] In 2012 OTC triptans increased by 19% in current value terms to reach GBP7 million.
USPRwire, Wed May 15 2013] Towards the end of the review period, all triptans remained Rx in Kazakhstan.
ClickPress, Wed May 01 2013] In 2012 all drugs classified as triptans remained Rx in Azerbaijan.
In 155 menstrual migraine attacks treated in double-blind fashion, the two triptans displayed similar short-term efficacy, as reflected in pain relief and pain-free episodes 2 and 4 hours post treatment.