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 (trō′pə-nĭn, trŏp′ə-)
A calcium-regulated protein, composed of three subunits, that is found in skeletal and cardiac muscle and regulates contraction by interacting with tropomyosin to control the binding of myosin to actin. Blood troponin levels are a biomarker for muscle damage, as in myocardial infarction.


a protein in muscle tissue that with tropomyosin is involved in the controlling of muscle contraction


(ˈtroʊ pə nɪn, ˈtrɒp ə-)

a protein of muscle tissue that binds calcium ions and is involved in contraction.
[1965–70; tropo(myosin) (see tropo-, myosin)]
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References in periodicals archive ?
The odds ratio for the combined end point of death or acute MI with a positive troponin T or I was 3.
using pooled data from 5 cohort studies recently reported lower sensitivities for both high-sensitivity troponin T at 94.
Serial high sensitivity cardiac troponin T measurement in acute heart failure: insights from the RELAX-AHF study.
Both troponin tests had poor sensitivity at 6 hours: 62% for the troponin T test and 58% for the troponin I test.
The extent of coronary atherosclerosis is associated with increasing circulating levels of high sensitive cardiac troponin T.
10-13) In fact, both troponin T and I are sensitive enough to detect microinfarction that may not be apparent on the ECG or by using other cardiac markers--such as CK or CK-MB.
Troponin T measurements at enrollment were examined for use in risk stratification in a GUSTO IIa substudy, using an outcome of 30-day mortality for 801 patients with acute coronary syndromes.
Raised troponin T in inclusion body myositis is common and serum levels are persistent over time.
Innovative technology such as mini-column separation methods (in the '70s and early '80s) for quantitative measurement of CK-MB and automated electrophoretic separation of CK-MB into two isoforms (in the '90s) have played vital roles in the development of our current automated enzyme immunoassays, which utilize highly sensitive and specific monoclonal antibodies to capture and detect CK-MB, myoglobin, troponin T, and troponin I.
Multibiomarker riskstratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death.
High-sensitivity troponin T concentrations in acute chest pain patients evaluated with cardiac computed tomography.