Umbelliferone


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Um`bel`lif´er`one


n.1.(Chem.) A tasteless white crystalline substance, C9H6O3, found in the bark of a certain plant (Daphne Mezereum), and also obtained by the distillation of certain gums from the Umbelliferæ, as galbanum, asafetida, etc. It is analogous to coumarin. Called also hydroxy-coumarin. Its strong fluorescence under ultraviolet light makes it useful in analytical biochemistry, as, for exmple, to detect phosphatase activity by hydrolysis of umbelliferyl phosphate.
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Results shown here discovered that quinoa is a excellent source of oxyprenylated umbelliferone and ferulic acid derivatives (Fiorito et al, 2019).
Both [lambda]-bisabolol,bisabolol oxides A and B and chamazulene or azulenesse, farnesene and spiro-ether quiterpene lactones, glycosides, hydroxycoumarins, flavanoids (apigenin, luteolin, patuletin, and quercetin), coumarins (herniarin and umbelliferone), terpenoids, and mucilage are considered to be the major bio-active ingredients.
Possible involvement of Nrf2 and PPAR[gamma] up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity.
The dried roots of Sophorae Radix contain flavonoids, such as kuraridin, kurarinone, isokurarinine, norkurarinone, pterocarpin, formononetin, trifolirhizin, daidzein, umbelliferone, maackiain, kuraridinol, kurarinol, neo-kurinol, and norkurarinol [13, 14].
All other compounds (4-11) were isolated for the first time from this plant which included a benzofuran derivative, cnidioside A (4); three flavonoid derivatives, quercetin 3-O-[beta]-D-glucopyranoside (5), rutin (6), and 4'-0-methylquercetin 3-O-[beta]-D-glucopyranoside (7); two coumarin derivatives, scopoletin (8) and umbelliferone (9); a phenylpropene derivative, eugenol 4-O-[beta]-D-glucopyranoside (10), and a eudesmane sesquiterpene glucoside, pumilaside A (11).
Nanjangud rasa bale) flower extract and its constituents Umbelliferone and Lupeol on [alpha]-glucosidase, aldose reductase and glycation at multiple stages," South African Journal of Botany, vol.
Hussein, "Possible involvement of Nrf2 and PPAR[gamma] upregulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity," Biomedicine & Pharmacotherapy, vol.
These were [beta]-sitosterol, apigenin, umbelliferone, 4-4,5,7-trihydroxyflavone, kaempferol, quercetin, caffeic acid, and gallic acid (40 [micro]L of 50 mg/mL).
Ma, "Umbelliferone reverses depression-like behavior in chronic unpredictable mild stress-induced rats by attenuating neuronal apoptosis via regulating ROCK/Akt pathway," Behavioural Brain Research, vol.
Abstract: The chloroform fraction of Potentilla evestita led to the isolation of three compounds which were characterized as Acacetin 1, Chrysin 2 and Umbelliferone 3.