Vinca alkaloids


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Related to Vinca alkaloids: vinblastine, vincristine, paclitaxel, Taxanes

Vinca alkaloids

Cytotoxic drugs used to prevent the replication of cells.
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Born on September 23, 1917, Dr Asima Chatterjee has various contributions on the research of vinca alkaloids and the development of anti-epileptic and anti-malarial drugs.
Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells.
APP-111 is a platform technology that may have activity in other tumor types that have previously responded to taxanes or vinca alkaloids.
ATMs belong to a class of anti-cancer drug known as anti-mitotics, including the current taxanes and vinca alkaloids.
These include the taxanes (paclitaxel, docetaxel) and the vinca alkaloids (vincristine, vinblastine).
These drugs include vinca alkaloids, platinum-based drugs such as cisplatin, oxaliplatin and carboplatin, and the taxanes docetaxel and paclitaxel.
Chemotherapy and Targeted Agents That May increase Risk of Cardiotoxicity Chemotherapy * Anthracyclines * 5-fluorouracil/capecitbine * Cyclophosphamide/ifosphamide * Paclitaxel/docetaxel * Cisplatin * Mitomycin C * Busulfan * Bleomycin * Mitoxantrone * Etoposide * Vinca alkaloids Targeted Therapies * Trastuzumab * Lapatinib * Sunitinib * Sorafenib * Rituximab * Imatinib mesylate * Bevacizumab * Interferons/interleukins * Arsenic trioxide Note.